Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ANN21623.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)    
Predicted Functional Partners:
ANN15613.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.994
ANN19777.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.977
ANN22159.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.977
ANN22158.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.976
ANN19547.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.973
ANN17807.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.926
ANN22136.1
Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.926
ANN14287.1
Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.740
ANN15612.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.739
ANN19766.1
Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.668
Your Current Organism:
Amycolatopsis orientalis
NCBI taxonomy Id: 31958
Other names: A. orientalis, ATCC 19795, Actinoplanes sp. ATCC 53771, Amycolatopsis orientalis orientalis, Amycolatopsis orientalis subsp. orientalis, CIP 107113, DSM 40040, IFO 12806, IMSNU 20058, ISP 5040, JCM 4235, JCM 4600, KCTC 9412, NBRC 12806, NRRL 2450, Nocardia orientalis, Streptomyces orientalis, UNIQEM 181, VKM Ac-866
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