close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANN15613.1DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)    
Predicted Functional Partners:
ANN21623.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.994
ANN22136.1
Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.976
ANN17807.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.934
ANN19781.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.743
ANN15612.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.671
ANN19969.1
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
     0.642
ANN19548.1
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
     0.606
ANN19549.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.507
ANN22387.1
Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.471
ANN20721.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.468
Your Current Organism:
Amycolatopsis orientalis
NCBI taxonomy Id: 31958
Other names: A. orientalis, ATCC 19795, Actinoplanes sp. ATCC 53771, Amycolatopsis orientalis orientalis, Amycolatopsis orientalis subsp. orientalis, CIP 107113, DSM 40040, IFO 12806, IMSNU 20058, ISP 5040, JCM 4235, JCM 4600, KCTC 9412, NBRC 12806, NRRL 2450, Nocardia orientalis, Streptomyces orientalis, UNIQEM 181, VKM Ac-866
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