STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANN15938.1Transcriptional regulator, SARP family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (939 aa)    
Predicted Functional Partners:
ANN18898.1
PAS sensor protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.611
ANN17437.1
Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.566
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.545
alaS
alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.544
htpG
Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity.
  
 0.543
ANN17915.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.529
ANN18886.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 0.524
ANN22322.1
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.522
ANN17979.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.504
ANN21087.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
   
 0.500
Your Current Organism:
Amycolatopsis orientalis
NCBI taxonomy Id: 31958
Other names: A. orientalis, ATCC 19795, Actinoplanes sp. ATCC 53771, Amycolatopsis orientalis orientalis, Amycolatopsis orientalis subsp. orientalis, CIP 107113, DSM 40040, IFO 12806, IMSNU 20058, ISP 5040, JCM 4235, JCM 4600, KCTC 9412, NBRC 12806, NRRL 2450, Nocardia orientalis, Streptomyces orientalis, UNIQEM 181, VKM Ac-866
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.