STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANN16569.14,5-9,10-diseco-3-hydroxy-5,9, 17-trioxoandrosta-1(10),2-diene-4-oate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)    
Predicted Functional Partners:
ANN16570.1
2,3-dihydroxybiphenyl 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.994
ANN16568.1
Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.936
ANN16580.1
Fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.928
ANN16565.1
3-ketosteroid-9-alpha-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.862
ANN16571.1
Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.832
ANN16567.1
23S rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.793
ANN16566.1
3-ketosteroid-delta-1-dehydrogenase; Initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.741
ANN16614.1
acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; in Mycobacterium may be involved in virulence; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.701
ANN16563.1
3-ketosteroid-9-alpha-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.694
ANN19811.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.668
Your Current Organism:
Amycolatopsis orientalis
NCBI taxonomy Id: 31958
Other names: A. orientalis, ATCC 19795, Actinoplanes sp. ATCC 53771, Amycolatopsis orientalis orientalis, Amycolatopsis orientalis subsp. orientalis, CIP 107113, DSM 40040, IFO 12806, IMSNU 20058, ISP 5040, JCM 4235, JCM 4600, KCTC 9412, NBRC 12806, NRRL 2450, Nocardia orientalis, Streptomyces orientalis, UNIQEM 181, VKM Ac-866
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