STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANN16666.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)    
Predicted Functional Partners:
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
       0.857
ANN16663.1
dUTPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.818
ANN16664.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.765
rbpA-2
Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
  
     0.728
ANN17556.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.722
ANN20297.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.705
ANN16440.1
DNA repair ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.704
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.696
ANN14501.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.695
ANN19621.1
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.687
Your Current Organism:
Amycolatopsis orientalis
NCBI taxonomy Id: 31958
Other names: A. orientalis, ATCC 19795, Actinoplanes sp. ATCC 53771, Amycolatopsis orientalis orientalis, Amycolatopsis orientalis subsp. orientalis, CIP 107113, DSM 40040, IFO 12806, IMSNU 20058, ISP 5040, JCM 4235, JCM 4600, KCTC 9412, NBRC 12806, NRRL 2450, Nocardia orientalis, Streptomyces orientalis, UNIQEM 181, VKM Ac-866
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