STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANN18813.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (814 aa)    
Predicted Functional Partners:
ANN19778.1
SARP family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.807
ANN22162.1
SARP family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.746
htpG
Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity.
  
 0.541
alaS
alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.524
ANN18148.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.501
ANN21087.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.494
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.489
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.476
ANN17907.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 0.469
ANN20807.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.469
Your Current Organism:
Amycolatopsis orientalis
NCBI taxonomy Id: 31958
Other names: A. orientalis, ATCC 19795, Actinoplanes sp. ATCC 53771, Amycolatopsis orientalis orientalis, Amycolatopsis orientalis subsp. orientalis, CIP 107113, DSM 40040, IFO 12806, IMSNU 20058, ISP 5040, JCM 4235, JCM 4600, KCTC 9412, NBRC 12806, NRRL 2450, Nocardia orientalis, Streptomyces orientalis, UNIQEM 181, VKM Ac-866
Server load: low (26%) [HD]