| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CMS0239 | cpdA | CMS0239 | CMS0240 | Putative N-acetylglucosamine-6-phosphate deacetylase; Belongs to the HAD-like hydrolase superfamily. | Putative phosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.533 |
| CMS1446 | adk | CMS1446 | CMS0303 | Putative secreted 5'-nucleotidase; Possible degradation of extracellular 5'-nucleotides for nutritional needs. May be sortase-sorted; Belongs to the 5'-nucleotidase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.900 |
| CMS1446 | apt | CMS1446 | CMS1178 | Putative secreted 5'-nucleotidase; Possible degradation of extracellular 5'-nucleotides for nutritional needs. May be sortase-sorted; Belongs to the 5'-nucleotidase family. | Adenine phosphoribosiltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.915 |
| CMS1446 | apt-2 | CMS1446 | CMS2395 | Putative secreted 5'-nucleotidase; Possible degradation of extracellular 5'-nucleotides for nutritional needs. May be sortase-sorted; Belongs to the 5'-nucleotidase family. | Adenine phosphoribosyltransferase. | 0.915 |
| CMS1446 | cpdA | CMS1446 | CMS0240 | Putative secreted 5'-nucleotidase; Possible degradation of extracellular 5'-nucleotides for nutritional needs. May be sortase-sorted; Belongs to the 5'-nucleotidase family. | Putative phosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.910 |
| CMS1446 | purB | CMS1446 | CMS3085 | Putative secreted 5'-nucleotidase; Possible degradation of extracellular 5'-nucleotides for nutritional needs. May be sortase-sorted; Belongs to the 5'-nucleotidase family. | Adenylosuccinate lyase. | 0.914 |
| adk | CMS1446 | CMS0303 | CMS1446 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Putative secreted 5'-nucleotidase; Possible degradation of extracellular 5'-nucleotides for nutritional needs. May be sortase-sorted; Belongs to the 5'-nucleotidase family. | 0.900 |
| adk | apt | CMS0303 | CMS1178 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenine phosphoribosiltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.929 |
| adk | apt-2 | CMS0303 | CMS2395 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenine phosphoribosyltransferase. | 0.929 |
| adk | cpdA | CMS0303 | CMS0240 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Putative phosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.900 |
| adk | purB | CMS0303 | CMS3085 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenylosuccinate lyase. | 0.948 |
| apt | CMS1446 | CMS1178 | CMS1446 | Adenine phosphoribosiltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative secreted 5'-nucleotidase; Possible degradation of extracellular 5'-nucleotides for nutritional needs. May be sortase-sorted; Belongs to the 5'-nucleotidase family. | 0.915 |
| apt | adk | CMS1178 | CMS0303 | Adenine phosphoribosiltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.929 |
| apt | apt-2 | CMS1178 | CMS2395 | Adenine phosphoribosiltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenine phosphoribosyltransferase. | 0.924 |
| apt | cpdA | CMS1178 | CMS0240 | Adenine phosphoribosiltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative phosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.904 |
| apt | purB | CMS1178 | CMS3085 | Adenine phosphoribosiltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate lyase. | 0.951 |
| apt-2 | CMS1446 | CMS2395 | CMS1446 | Adenine phosphoribosyltransferase. | Putative secreted 5'-nucleotidase; Possible degradation of extracellular 5'-nucleotides for nutritional needs. May be sortase-sorted; Belongs to the 5'-nucleotidase family. | 0.915 |
| apt-2 | adk | CMS2395 | CMS0303 | Adenine phosphoribosyltransferase. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.929 |
| apt-2 | apt | CMS2395 | CMS1178 | Adenine phosphoribosyltransferase. | Adenine phosphoribosiltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.924 |
| apt-2 | cpdA | CMS2395 | CMS0240 | Adenine phosphoribosyltransferase. | Putative phosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.904 |