| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CMS0243 | polA-2 | CMS0243 | CMS1999 | Putative ATP-dependent DNA helicase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.845 |
| CMS0243 | smc | CMS0243 | CMS0749 | Putative ATP-dependent DNA helicase. | Putative chromosome structure maintenance protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.457 |
| CMS0243 | topA | CMS0243 | CMS0187 | Putative ATP-dependent DNA helicase. | Probable DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing [...] | 0.734 |
| CMS0748 | ftsY | CMS0748 | CMS0750 | Conserved hypothetical protein. | Signal recognition particle receptor. | 0.494 |
| CMS0748 | smc | CMS0748 | CMS0749 | Conserved hypothetical protein. | Putative chromosome structure maintenance protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.541 |
| CMS1253 | CMS1254 | CMS1253 | CMS1254 | Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.999 |
| CMS1253 | smc | CMS1253 | CMS0749 | Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | Putative chromosome structure maintenance protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.984 |
| CMS1254 | CMS1253 | CMS1254 | CMS1253 | Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.999 |
| CMS1254 | smc | CMS1254 | CMS0749 | Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | Putative chromosome structure maintenance protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.938 |
| ffh | ftsY | CMS0751 | CMS0750 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Signal recognition particle receptor. | 0.999 |
| ffh | secA | CMS0751 | CMS0673 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.981 |
| ffh | smc | CMS0751 | CMS0749 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Putative chromosome structure maintenance protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.744 |
| ffh | topA | CMS0751 | CMS0187 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Probable DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing [...] | 0.450 |
| ftsY | CMS0748 | CMS0750 | CMS0748 | Signal recognition particle receptor. | Conserved hypothetical protein. | 0.494 |
| ftsY | ffh | CMS0750 | CMS0751 | Signal recognition particle receptor. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.999 |
| ftsY | polA-2 | CMS0750 | CMS1999 | Signal recognition particle receptor. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.525 |
| ftsY | secA | CMS0750 | CMS0673 | Signal recognition particle receptor. | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.968 |
| ftsY | smc | CMS0750 | CMS0749 | Signal recognition particle receptor. | Putative chromosome structure maintenance protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.909 |
| parB | polA-2 | CMS3107 | CMS1999 | Probable chromosome partitioning protein ParB; Belongs to the ParB family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.567 |
| parB | smc | CMS3107 | CMS0749 | Probable chromosome partitioning protein ParB; Belongs to the ParB family. | Putative chromosome structure maintenance protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.475 |