| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CMS0612 | CMS2021 | CMS0612 | CMS2021 | Putative RNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | Conserved hypothetical Sun-family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.711 |
| CMS2021 | CMS0612 | CMS2021 | CMS0612 | Conserved hypothetical Sun-family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Putative RNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.711 |
| CMS2021 | fmt | CMS2021 | CMS2022 | Conserved hypothetical Sun-family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.982 |
| CMS2021 | priA-2 | CMS2021 | CMS2023 | Conserved hypothetical Sun-family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Putative primosomal protein n' (replication factor y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.739 |
| CMS2021 | rpe | CMS2021 | CMS2020 | Conserved hypothetical Sun-family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | PS00454 FKBP-type peptidyl-prolyl cis-trans isomerase signature 2; Belongs to the ribulose-phosphate 3-epimerase family. | 0.930 |
| CMS2021 | rplC | CMS2021 | CMS0283 | Conserved hypothetical Sun-family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.730 |
| CMS2021 | rplJ | CMS2021 | CMS0115 | Conserved hypothetical Sun-family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.757 |
| CMS2021 | rplR | CMS2021 | CMS0298 | Conserved hypothetical Sun-family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.740 |
| CMS2021 | rplW | CMS2021 | CMS0285 | Conserved hypothetical Sun-family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 50s ribosomal protein l23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.717 |
| CMS2021 | rplX | CMS2021 | CMS0294 | Conserved hypothetical Sun-family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.729 |
| CMS2021 | rpmD | CMS2021 | CMS0300 | Conserved hypothetical Sun-family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 50S ribosomal protein L30. | 0.764 |
| fmt | CMS2021 | CMS2022 | CMS2021 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Conserved hypothetical Sun-family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.982 |
| fmt | priA-2 | CMS2022 | CMS2023 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Putative primosomal protein n' (replication factor y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.904 |
| fmt | rpe | CMS2022 | CMS2020 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | PS00454 FKBP-type peptidyl-prolyl cis-trans isomerase signature 2; Belongs to the ribulose-phosphate 3-epimerase family. | 0.719 |
| priA-2 | CMS2021 | CMS2023 | CMS2021 | Putative primosomal protein n' (replication factor y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | Conserved hypothetical Sun-family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.739 |
| priA-2 | fmt | CMS2023 | CMS2022 | Putative primosomal protein n' (replication factor y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.904 |
| priA-2 | rpe | CMS2023 | CMS2020 | Putative primosomal protein n' (replication factor y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | PS00454 FKBP-type peptidyl-prolyl cis-trans isomerase signature 2; Belongs to the ribulose-phosphate 3-epimerase family. | 0.437 |
| rpe | CMS2021 | CMS2020 | CMS2021 | PS00454 FKBP-type peptidyl-prolyl cis-trans isomerase signature 2; Belongs to the ribulose-phosphate 3-epimerase family. | Conserved hypothetical Sun-family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.930 |
| rpe | fmt | CMS2020 | CMS2022 | PS00454 FKBP-type peptidyl-prolyl cis-trans isomerase signature 2; Belongs to the ribulose-phosphate 3-epimerase family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.719 |
| rpe | priA-2 | CMS2020 | CMS2023 | PS00454 FKBP-type peptidyl-prolyl cis-trans isomerase signature 2; Belongs to the ribulose-phosphate 3-epimerase family. | Putative primosomal protein n' (replication factor y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.437 |