| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CMS0127 | CMS2433 | CMS0127 | CMS2433 | Putative cystathionine beta-synthase. | Putative amino acid dehydratase. | 0.941 |
| CMS0127 | glyA | CMS0127 | CMS0586 | Putative cystathionine beta-synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.939 |
| CMS0127 | sdaA | CMS0127 | CMS2345 | Putative cystathionine beta-synthase. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.913 |
| CMS1932 | CMS2433 | CMS1932 | CMS2433 | Putative aldolase. | Putative amino acid dehydratase. | 0.942 |
| CMS1932 | glyA | CMS1932 | CMS0586 | Putative aldolase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.925 |
| CMS1932 | thrC | CMS1932 | CMS1478 | Putative aldolase. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.940 |
| CMS2433 | CMS0127 | CMS2433 | CMS0127 | Putative amino acid dehydratase. | Putative cystathionine beta-synthase. | 0.941 |
| CMS2433 | CMS1932 | CMS2433 | CMS1932 | Putative amino acid dehydratase. | Putative aldolase. | 0.942 |
| CMS2433 | glyA | CMS2433 | CMS0586 | Putative amino acid dehydratase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.955 |
| CMS2433 | ilvB | CMS2433 | CMS1414 | Putative amino acid dehydratase. | Acetolactate synthase. | 0.974 |
| CMS2433 | ilvD | CMS2433 | CMS1413 | Putative amino acid dehydratase. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.948 |
| CMS2433 | ilvE | CMS2433 | CMS1425 | Putative amino acid dehydratase. | Branched-chain amino acid aminotransferase. | 0.941 |
| CMS2433 | ilvH | CMS2433 | CMS1415 | Putative amino acid dehydratase. | Acetolactate synthase small subunit. | 0.981 |
| CMS2433 | leuB | CMS2433 | CMS1424 | Putative amino acid dehydratase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.955 |
| CMS2433 | sdaA | CMS2433 | CMS2345 | Putative amino acid dehydratase. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.951 |
| CMS2433 | thrC | CMS2433 | CMS1478 | Putative amino acid dehydratase. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.957 |
| glyA | CMS0127 | CMS0586 | CMS0127 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative cystathionine beta-synthase. | 0.939 |
| glyA | CMS1932 | CMS0586 | CMS1932 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative aldolase. | 0.925 |
| glyA | CMS2433 | CMS0586 | CMS2433 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative amino acid dehydratase. | 0.955 |
| glyA | sdaA | CMS0586 | CMS2345 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.980 |