| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CMS2578 | CMS2579 | CMS2578 | CMS2579 | Putative phosphoglycerate mutase related enzyme. | Putative lipoprotein. | 0.962 |
| CMS2578 | hemL | CMS2578 | CMS2838 | Putative phosphoglycerate mutase related enzyme. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.768 |
| CMS2579 | CMS2578 | CMS2579 | CMS2578 | Putative lipoprotein. | Putative phosphoglycerate mutase related enzyme. | 0.962 |
| CMS2579 | hemA | CMS2579 | CMS2850 | Putative lipoprotein. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.572 |
| CMS2579 | hemE | CMS2579 | CMS2849 | Putative lipoprotein. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.633 |
| CMS2579 | hemL | CMS2579 | CMS2838 | Putative lipoprotein. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.817 |
| CMS2840 | hemA | CMS2840 | CMS2850 | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.837 |
| CMS2840 | hemB | CMS2840 | CMS2839 | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.988 |
| CMS2840 | hemC | CMS2840 | CMS2841 | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
| CMS2840 | hemE | CMS2840 | CMS2849 | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.953 |
| CMS2840 | hemH | CMS2840 | CMS2842 | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.870 |
| CMS2840 | hemL | CMS2840 | CMS2838 | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.841 |
| CMS2840 | hemY | CMS2840 | CMS2848 | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.559 |
| hemA | CMS2579 | CMS2850 | CMS2579 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Putative lipoprotein. | 0.572 |
| hemA | CMS2840 | CMS2850 | CMS2840 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.837 |
| hemA | hemB | CMS2850 | CMS2839 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.932 |
| hemA | hemC | CMS2850 | CMS2841 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.993 |
| hemA | hemE | CMS2850 | CMS2849 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.916 |
| hemA | hemH | CMS2850 | CMS2842 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.706 |
| hemA | hemL | CMS2850 | CMS2838 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.993 |