| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CMS2840 | CMS2843 | CMS2840 | CMS2843 | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Putative heme synthetase; Weak but full length match to Q6AB01_PROAC. | 0.635 |
| CMS2840 | CMS2844 | CMS2840 | CMS2844 | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Putative integral membrane protein. | 0.472 |
| CMS2840 | CMS2845 | CMS2840 | CMS2845 | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Putative membrane protein. | 0.459 |
| CMS2840 | CMS2846 | CMS2840 | CMS2846 | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Putative integral membrane protein. | 0.466 |
| CMS2840 | hemB | CMS2840 | CMS2839 | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.988 |
| CMS2840 | hemC | CMS2840 | CMS2841 | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
| CMS2840 | hemE | CMS2840 | CMS2849 | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.953 |
| CMS2840 | hemH | CMS2840 | CMS2842 | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.870 |
| CMS2840 | hemL | CMS2840 | CMS2838 | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.841 |
| CMS2840 | hemY | CMS2840 | CMS2848 | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.559 |
| CMS2843 | CMS2840 | CMS2843 | CMS2840 | Putative heme synthetase; Weak but full length match to Q6AB01_PROAC. | Putative uroporphyrin-III c-methyltransferase/uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.635 |
| CMS2843 | CMS2844 | CMS2843 | CMS2844 | Putative heme synthetase; Weak but full length match to Q6AB01_PROAC. | Putative integral membrane protein. | 0.675 |
| CMS2843 | CMS2845 | CMS2843 | CMS2845 | Putative heme synthetase; Weak but full length match to Q6AB01_PROAC. | Putative membrane protein. | 0.630 |
| CMS2843 | CMS2846 | CMS2843 | CMS2846 | Putative heme synthetase; Weak but full length match to Q6AB01_PROAC. | Putative integral membrane protein. | 0.631 |
| CMS2843 | hemB | CMS2843 | CMS2839 | Putative heme synthetase; Weak but full length match to Q6AB01_PROAC. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.713 |
| CMS2843 | hemC | CMS2843 | CMS2841 | Putative heme synthetase; Weak but full length match to Q6AB01_PROAC. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.711 |
| CMS2843 | hemE | CMS2843 | CMS2849 | Putative heme synthetase; Weak but full length match to Q6AB01_PROAC. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.688 |
| CMS2843 | hemH | CMS2843 | CMS2842 | Putative heme synthetase; Weak but full length match to Q6AB01_PROAC. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.989 |
| CMS2843 | hemL | CMS2843 | CMS2838 | Putative heme synthetase; Weak but full length match to Q6AB01_PROAC. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.631 |
| CMS2843 | hemY | CMS2843 | CMS2848 | Putative heme synthetase; Weak but full length match to Q6AB01_PROAC. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.723 |