| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CMS2929 | CMS2930 | CMS2929 | CMS2930 | Putative integral membrane protein. | Putative AraC-family transcriptional regulator. | 0.773 |
| CMS2929 | gcvP | CMS2929 | CMS2222 | Putative integral membrane protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.945 |
| CMS2929 | guaA | CMS2929 | CMS0540 | Putative integral membrane protein. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.799 |
| CMS2929 | purB | CMS2929 | CMS3085 | Putative integral membrane protein. | Adenylosuccinate lyase. | 0.772 |
| CMS2929 | purC | CMS2929 | CMS1027 | Putative integral membrane protein. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.773 |
| CMS2929 | purE | CMS2929 | CMS0623 | Putative integral membrane protein. | Phosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.714 |
| CMS2929 | purF | CMS2929 | CMS1031 | Putative integral membrane protein. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.732 |
| CMS2929 | purH | CMS2929 | CMS2592 | Putative integral membrane protein. | Bifunctional purine biosynthesis protein. | 0.731 |
| CMS2929 | purK | CMS2929 | CMS0622 | Putative integral membrane protein. | Phosphoribosylaminoimidazole carboxylase ATPase subunit PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.714 |
| CMS2929 | purS | CMS2929 | CMS2248 | Putative integral membrane protein. | Conserved hypothetical protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer [...] | 0.733 |
| CMS2930 | CMS2929 | CMS2930 | CMS2929 | Putative AraC-family transcriptional regulator. | Putative integral membrane protein. | 0.773 |
| gcvP | CMS2929 | CMS2222 | CMS2929 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Putative integral membrane protein. | 0.945 |
| gcvP | guaA | CMS2222 | CMS0540 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.786 |
| gcvP | purB | CMS2222 | CMS3085 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Adenylosuccinate lyase. | 0.422 |
| gcvP | purC | CMS2222 | CMS1027 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.698 |
| gcvP | purE | CMS2222 | CMS0623 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.479 |
| gcvP | purF | CMS2222 | CMS1031 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.749 |
| gcvP | purH | CMS2222 | CMS2592 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Bifunctional purine biosynthesis protein. | 0.760 |
| guaA | CMS2929 | CMS0540 | CMS2929 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Putative integral membrane protein. | 0.799 |
| guaA | gcvP | CMS0540 | CMS2222 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.786 |