| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| apt | apt-2 | CMS1178 | CMS2395 | Adenine phosphoribosiltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenine phosphoribosyltransferase. | 0.924 |
| apt | purA | CMS1178 | CMS2142 | Adenine phosphoribosiltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypothetical protein (pseudogene); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.591 |
| apt | purB | CMS1178 | CMS3085 | Adenine phosphoribosiltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate lyase. | 0.963 |
| apt | purE | CMS1178 | CMS0623 | Adenine phosphoribosiltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.407 |
| apt | purH | CMS1178 | CMS2592 | Adenine phosphoribosiltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Bifunctional purine biosynthesis protein. | 0.945 |
| apt | purK | CMS1178 | CMS0622 | Adenine phosphoribosiltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylaminoimidazole carboxylase ATPase subunit PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.405 |
| apt-2 | apt | CMS2395 | CMS1178 | Adenine phosphoribosyltransferase. | Adenine phosphoribosiltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.924 |
| apt-2 | purA | CMS2395 | CMS2142 | Adenine phosphoribosyltransferase. | Hypothetical protein (pseudogene); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.591 |
| apt-2 | purB | CMS2395 | CMS3085 | Adenine phosphoribosyltransferase. | Adenylosuccinate lyase. | 0.963 |
| apt-2 | purE | CMS2395 | CMS0623 | Adenine phosphoribosyltransferase. | Phosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.407 |
| apt-2 | purH | CMS2395 | CMS2592 | Adenine phosphoribosyltransferase. | Bifunctional purine biosynthesis protein. | 0.945 |
| apt-2 | purK | CMS2395 | CMS0622 | Adenine phosphoribosyltransferase. | Phosphoribosylaminoimidazole carboxylase ATPase subunit PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.405 |
| purA | apt | CMS2142 | CMS1178 | Hypothetical protein (pseudogene); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Adenine phosphoribosiltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.591 |
| purA | apt-2 | CMS2142 | CMS2395 | Hypothetical protein (pseudogene); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Adenine phosphoribosyltransferase. | 0.591 |
| purA | purB | CMS2142 | CMS3085 | Hypothetical protein (pseudogene); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Adenylosuccinate lyase. | 0.998 |
| purA | purC | CMS2142 | CMS1027 | Hypothetical protein (pseudogene); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.964 |
| purA | purD | CMS2142 | CMS1028 | Hypothetical protein (pseudogene); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Phosphoribosylamine-glycine ligase; OrderedLocusNames=SCO4068; ORFNames=SCD25.04; Belongs to the GARS family. | 0.704 |
| purA | purE | CMS2142 | CMS0623 | Hypothetical protein (pseudogene); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Phosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.951 |
| purA | purF | CMS2142 | CMS1031 | Hypothetical protein (pseudogene); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.584 |
| purA | purH | CMS2142 | CMS2592 | Hypothetical protein (pseudogene); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Bifunctional purine biosynthesis protein. | 0.981 |