| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| prfC | rplI | CMS3093 | CMS3096 | Peptide chain release factor 3 (RF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | 50S ribosomal protein L9; Binds to the 23S rRNA. | 0.705 |
| prfC | rplL | CMS3093 | CMS0116 | Peptide chain release factor 3 (RF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | 50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.725 |
| prfC | rplM | CMS3093 | CMS0320 | Peptide chain release factor 3 (RF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.701 |
| prfC | rplQ | CMS3093 | CMS0317 | Peptide chain release factor 3 (RF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | 50S ribosomal protein L17. | 0.708 |
| prfC | rplS | CMS3093 | CMS0761 | Peptide chain release factor 3 (RF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.745 |
| prfC | rplT | CMS3093 | CMS1223 | Peptide chain release factor 3 (RF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.741 |
| prfC | rplU | CMS3093 | CMS1816 | Peptide chain release factor 3 (RF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.690 |
| prfC | rpmA | CMS3093 | CMS1815 | Peptide chain release factor 3 (RF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | 50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. | 0.797 |
| prfC | rpmF | CMS3093 | CMS0745 | Peptide chain release factor 3 (RF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | 50s ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.711 |
| prfC | rpmG | CMS3093 | CMS3071 | Peptide chain release factor 3 (RF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | 50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. | 0.756 |
| rplI | prfC | CMS3096 | CMS3093 | 50S ribosomal protein L9; Binds to the 23S rRNA. | Peptide chain release factor 3 (RF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. | 0.705 |
| rplI | rplL | CMS3096 | CMS0116 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.992 |
| rplI | rplM | CMS3096 | CMS0320 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.993 |
| rplI | rplQ | CMS3096 | CMS0317 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 50S ribosomal protein L17. | 0.993 |
| rplI | rplS | CMS3096 | CMS0761 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.996 |
| rplI | rplT | CMS3096 | CMS1223 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.996 |
| rplI | rplU | CMS3096 | CMS1816 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.993 |
| rplI | rpmA | CMS3096 | CMS1815 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. | 0.992 |
| rplI | rpmF | CMS3096 | CMS0745 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 50s ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.971 |
| rplI | rpmG | CMS3096 | CMS3071 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. | 0.974 |
