STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRN65108.1D-alanyl transfer protein; Could be involved in the transport of activated D-alanine through the membrane. (399 aa)    
Predicted Functional Partners:
KRN65106.1
D-alanyl transfer protein.
 
 
 0.999
dltA
dltA protein; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP-binding enzyme [...]
 
  
 0.997
dltC
Hypothetical protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
 
 
 0.996
acpP
Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.909
KRN66100.1
Serine-type D-Ala-D-Ala carboxypeptidase.
 
  
 0.826
KRN65228.1
Alpha beta hydrolase superfamily protein.
 
     0.676
KRN66105.1
Hypothetical protein.
 
  
 0.624
KRN65881.1
Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family.
   
   0.481
KRN67327.1
Acetaldehyde dehydrogenase.
    
   0.478
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
       0.475
Your Current Organism:
Pediococcus cellicola
NCBI taxonomy Id: 319652
Other names: AS 1.3787, DSM 17757, JCM 14152, LMG 22956, LMG:22956, P. cellicola, Pediococcus cellicola Zhang et al. 2005, Pediococcus sp. Z-1, Pediococcus sp. Z-8, strain Z-8
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