STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SER78832.1Putative holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (146 aa)    
Predicted Functional Partners:
SER78804.1
Uncharacterized protein, UPF0297 family; Belongs to the UPF0297 family.
 
    0.965
SER78860.1
Uncharacterized protein YrzB, UPF0473 family; Belongs to the UPF0473 family.
  
    0.933
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  
 0.857
mutS2
DNA mismatch repair protein MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
       0.650
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
  
    0.570
SER41280.1
23S rRNA (guanosine2251-2'-O)-methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
  
  
 0.543
SER73318.1
Uncharacterized protein YnzC, UPF0291/DUF896 family.
  
    0.483
SER14274.1
Uncharacterized conserved protein YloU, alkaline shock protein (Asp23) family.
 
    0.442
SER78925.1
Thioredoxin; Belongs to the thioredoxin family.
       0.440
ruvA
Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
 
  
 0.430
Your Current Organism:
Pediococcus ethanolidurans
NCBI taxonomy Id: 319653
Other names: AS 1.3889, DSM 22301, LMG 23354, LMG:23354, P. ethanolidurans, Pediococcus ethanolidurans Liu et al. 2006, Pediococcus sp. Z-9, strain Z-9
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