STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SER85425.1DNA-entry nuclease. (321 aa)    
Predicted Functional Partners:
sigA
RNA polymerase primary sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.648
SER86385.1
Hypothetical protein.
  
     0.495
SER85401.1
Hypothetical protein.
       0.468
SER47908.1
Metal binding domain of Ada.
   
 0.439
dnaA
Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.425
SER87661.1
methylated-DNA-[protein]-cysteine S-methyltransferase.
  
  
 0.401
Your Current Organism:
Pediococcus ethanolidurans
NCBI taxonomy Id: 319653
Other names: AS 1.3889, DSM 22301, LMG 23354, LMG:23354, P. ethanolidurans, Pediococcus ethanolidurans Liu et al. 2006, Pediococcus sp. Z-9, strain Z-9
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.