STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dgeo_0195Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver: (1.8e-38) transcriptional regulatory protein-like: (2.9e-23); KEGG: dra:DR0781 response regulator, OmpR/PhoB family, ev=1e-121, 95% identity. (222 aa)    
Predicted Functional Partners:
Dgeo_0129
Histidine kinase; PFAM: ATP-binding region, ATPase-like: (3.3e-24) histidine kinase A-like: (1.9e-11); KEGG: dra:DR2244 sensory transduction histidine kinase, ev=6e-99, 82% identity.
 
  0.981
Dgeo_1269
PFAM: response regulator receiver: (1e-06) ATP-binding region, ATPase-like: (4.6e-35) histidine kinase A-like: (4.5e-14); KEGG: dra:DR1175 sensor histidine kinase/response regulator, ev=1e-162, 78% identity.
 
 
 0.933
Dgeo_1558
Periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like: (4.7e-33) histidine kinase A-like: (0.0025); KEGG: xoo:XOO1106 two-component system sensor protein, ev=6e-26, 36% identity.
 
 
 0.929
Dgeo_2214
Periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like: (1.6e-35) histidine kinase, HAMP region: (2.6e-13) histidine kinase A-like: (1.1e-06); KEGG: dra:DR2328 sensor histidine kinase, ev=1e-132, 58% identity.
 
   0.870
Dgeo_2344
Periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like: (5.3e-39) histidine kinase, HAMP region: (5.3e-07); KEGG: dra:DR2416 sensor histidine kinase, ev=1e-157, 65% identity.
 
   0.865
Dgeo_1625
Periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like: (2.1e-11) histidine kinase, HAMP region: (1.2e-05) histidine kinase A-like: (2.5e-06); KEGG: dra:DR0892 sensor histidine kinase, ev=1e-104, 60% identity.
 
   0.864
Dgeo_0088
Periplasmic sensor signal transduction histidine kinase containing HAMP domain; PFAM: ATP-binding region, ATPase-like: (3.8e-46) histidine kinase, HAMP region: (2.1e-15) histidine kinase A-like: (4.3e-12); KEGG: ttj:TTHA1723 sensor histidine kinase, ev=3e-95, 56% identity.
   0.857
Dgeo_2317
Periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like: (1.4e-41) histidine kinase, HAMP region: (4.9e-18) histidine kinase A-like: (1.1e-23); KEGG: dra:DR0744 sensor histidine kinase, ev=1e-176, 62% identity.
   0.856
Dgeo_1521
Periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like: (3.6e-38) histidine kinase, HAMP region: (9.7e-16) histidine kinase A-like: (1.8e-13); KEGG: det:DET1059 sensor histidine kinase, ev=3e-52, 37% identity.
   0.837
Dgeo_0908
Histidine kinase; PFAM: ATP-binding region, ATPase-like: (2.8e-40) histidine kinase A-like: (3.8e-13); KEGG: dra:DR0860 sensor histidine kinase, ev=1e-134, 65% identity.
 
 0.820
Your Current Organism:
Deinococcus geothermalis
NCBI taxonomy Id: 319795
Other names: D. geothermalis DSM 11300, Deinococcus geothermalis AG-3a, Deinococcus geothermalis CIP 105573, Deinococcus geothermalis DSM 11300, Deinococcus geothermalis str. DSM 11300, Deinococcus geothermalis strain DSM 11300
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