node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dgeo_0691 | Dgeo_0692 | Dgeo_0691 | Dgeo_0692 | PFAM: Disulphide bond formation protein DsbB: (8.7e-25); KEGG: dra:DR0754 hypothetical protein, ev=9e-46, 60% identity; Belongs to the DsbB family. | PFAM: DSBA oxidoreductase: (6e-07); KEGG: dra:DR0753 hypothetical protein, ev=6e-72, 63% identity. | 0.963 |
Dgeo_0691 | Dgeo_0693 | Dgeo_0691 | Dgeo_0693 | PFAM: Disulphide bond formation protein DsbB: (8.7e-25); KEGG: dra:DR0754 hypothetical protein, ev=9e-46, 60% identity; Belongs to the DsbB family. | KEGG: dra:DR1770 hypothetical protein, ev=3e-49, 50% identity. | 0.802 |
Dgeo_0691 | uvrA | Dgeo_0691 | Dgeo_0694 | PFAM: Disulphide bond formation protein DsbB: (8.7e-25); KEGG: dra:DR0754 hypothetical protein, ev=9e-46, 60% identity; Belongs to the DsbB family. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.809 |
Dgeo_0692 | Dgeo_0691 | Dgeo_0692 | Dgeo_0691 | PFAM: DSBA oxidoreductase: (6e-07); KEGG: dra:DR0753 hypothetical protein, ev=6e-72, 63% identity. | PFAM: Disulphide bond formation protein DsbB: (8.7e-25); KEGG: dra:DR0754 hypothetical protein, ev=9e-46, 60% identity; Belongs to the DsbB family. | 0.963 |
Dgeo_0692 | Dgeo_0693 | Dgeo_0692 | Dgeo_0693 | PFAM: DSBA oxidoreductase: (6e-07); KEGG: dra:DR0753 hypothetical protein, ev=6e-72, 63% identity. | KEGG: dra:DR1770 hypothetical protein, ev=3e-49, 50% identity. | 0.803 |
Dgeo_0692 | uvrA | Dgeo_0692 | Dgeo_0694 | PFAM: DSBA oxidoreductase: (6e-07); KEGG: dra:DR0753 hypothetical protein, ev=6e-72, 63% identity. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.802 |
Dgeo_0693 | Dgeo_0691 | Dgeo_0693 | Dgeo_0691 | KEGG: dra:DR1770 hypothetical protein, ev=3e-49, 50% identity. | PFAM: Disulphide bond formation protein DsbB: (8.7e-25); KEGG: dra:DR0754 hypothetical protein, ev=9e-46, 60% identity; Belongs to the DsbB family. | 0.802 |
Dgeo_0693 | Dgeo_0692 | Dgeo_0693 | Dgeo_0692 | KEGG: dra:DR1770 hypothetical protein, ev=3e-49, 50% identity. | PFAM: DSBA oxidoreductase: (6e-07); KEGG: dra:DR0753 hypothetical protein, ev=6e-72, 63% identity. | 0.803 |
Dgeo_0693 | uvrA | Dgeo_0693 | Dgeo_0694 | KEGG: dra:DR1770 hypothetical protein, ev=3e-49, 50% identity. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.810 |
Dgeo_0868 | ligA | Dgeo_0868 | Dgeo_0696 | PFAM: UvrD/REP helicase: (1.3e-196); KEGG: dra:DR1775 DNA helicase II, ev=0.0, 82% identity. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.746 |
Dgeo_0868 | recA | Dgeo_0868 | Dgeo_2138 | PFAM: UvrD/REP helicase: (1.3e-196); KEGG: dra:DR1775 DNA helicase II, ev=0.0, 82% identity. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.873 |
Dgeo_0868 | topA | Dgeo_0868 | Dgeo_2001 | PFAM: UvrD/REP helicase: (1.3e-196); KEGG: dra:DR1775 DNA helicase II, ev=0.0, 82% identity. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.757 |
Dgeo_0868 | uvrA | Dgeo_0868 | Dgeo_0694 | PFAM: UvrD/REP helicase: (1.3e-196); KEGG: dra:DR1775 DNA helicase II, ev=0.0, 82% identity. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.721 |
Dgeo_0868 | uvrB | Dgeo_0868 | Dgeo_1890 | PFAM: UvrD/REP helicase: (1.3e-196); KEGG: dra:DR1775 DNA helicase II, ev=0.0, 82% identity. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.989 |
Dgeo_0868 | uvrC | Dgeo_0868 | Dgeo_1124 | PFAM: UvrD/REP helicase: (1.3e-196); KEGG: dra:DR1775 DNA helicase II, ev=0.0, 82% identity. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.790 |
ligA | Dgeo_0868 | Dgeo_0696 | Dgeo_0868 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | PFAM: UvrD/REP helicase: (1.3e-196); KEGG: dra:DR1775 DNA helicase II, ev=0.0, 82% identity. | 0.746 |
ligA | mfd | Dgeo_0696 | Dgeo_0545 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Transcription factor CarD; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.558 |
ligA | recA | Dgeo_0696 | Dgeo_2138 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.436 |
ligA | topA | Dgeo_0696 | Dgeo_2001 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.587 |
ligA | uvrA | Dgeo_0696 | Dgeo_0694 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.588 |