node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dgeo_1750 | coaX | Dgeo_1750 | Dgeo_1749 | PFAM: AMP-dependent synthetase and ligase: (5.5e-117); KEGG: dra:DR0460 acetyl-CoA synthase, ev=0.0, 78% identity. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.606 |
Dgeo_2140 | Dgeo_2315 | Dgeo_2140 | Dgeo_2315 | TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase: (9.3e-34) Helix-turn-helix biotin operon repressor region: (3.4e-19); PFAM: biotin protein ligase-like: (5.6e-05) biotin/lipoate A/B protein ligase: (1.8e-16); KEGG: dra:DR2341 birA bifunctional protein, ev=1e-111, 69% identity. | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.509 |
Dgeo_2140 | coaD | Dgeo_2140 | Dgeo_0286 | TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase: (9.3e-34) Helix-turn-helix biotin operon repressor region: (3.4e-19); PFAM: biotin protein ligase-like: (5.6e-05) biotin/lipoate A/B protein ligase: (1.8e-16); KEGG: dra:DR2341 birA bifunctional protein, ev=1e-111, 69% identity. | Phosphopantetheine adenylyltransferase, CoaD; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.435 |
Dgeo_2140 | coaX | Dgeo_2140 | Dgeo_1749 | TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase: (9.3e-34) Helix-turn-helix biotin operon repressor region: (3.4e-19); PFAM: biotin protein ligase-like: (5.6e-05) biotin/lipoate A/B protein ligase: (1.8e-16); KEGG: dra:DR2341 birA bifunctional protein, ev=1e-111, 69% identity. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.830 |
Dgeo_2140 | panC | Dgeo_2140 | Dgeo_0670 | TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase: (9.3e-34) Helix-turn-helix biotin operon repressor region: (3.4e-19); PFAM: biotin protein ligase-like: (5.6e-05) biotin/lipoate A/B protein ligase: (1.8e-16); KEGG: dra:DR2341 birA bifunctional protein, ev=1e-111, 69% identity. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.637 |
Dgeo_2140 | panD | Dgeo_2140 | Dgeo_1422 | TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase: (9.3e-34) Helix-turn-helix biotin operon repressor region: (3.4e-19); PFAM: biotin protein ligase-like: (5.6e-05) biotin/lipoate A/B protein ligase: (1.8e-16); KEGG: dra:DR2341 birA bifunctional protein, ev=1e-111, 69% identity. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.606 |
Dgeo_2315 | Dgeo_2140 | Dgeo_2315 | Dgeo_2140 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase: (9.3e-34) Helix-turn-helix biotin operon repressor region: (3.4e-19); PFAM: biotin protein ligase-like: (5.6e-05) biotin/lipoate A/B protein ligase: (1.8e-16); KEGG: dra:DR2341 birA bifunctional protein, ev=1e-111, 69% identity. | 0.509 |
Dgeo_2315 | coaD | Dgeo_2315 | Dgeo_0286 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase, CoaD; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.940 |
Dgeo_2315 | coaX | Dgeo_2315 | Dgeo_1749 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.925 |
Dgeo_2315 | panC | Dgeo_2315 | Dgeo_0670 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.902 |
coaD | Dgeo_2140 | Dgeo_0286 | Dgeo_2140 | Phosphopantetheine adenylyltransferase, CoaD; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase: (9.3e-34) Helix-turn-helix biotin operon repressor region: (3.4e-19); PFAM: biotin protein ligase-like: (5.6e-05) biotin/lipoate A/B protein ligase: (1.8e-16); KEGG: dra:DR2341 birA bifunctional protein, ev=1e-111, 69% identity. | 0.435 |
coaD | Dgeo_2315 | Dgeo_0286 | Dgeo_2315 | Phosphopantetheine adenylyltransferase, CoaD; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.940 |
coaD | coaX | Dgeo_0286 | Dgeo_1749 | Phosphopantetheine adenylyltransferase, CoaD; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.960 |
coaX | Dgeo_1750 | Dgeo_1749 | Dgeo_1750 | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | PFAM: AMP-dependent synthetase and ligase: (5.5e-117); KEGG: dra:DR0460 acetyl-CoA synthase, ev=0.0, 78% identity. | 0.606 |
coaX | Dgeo_2140 | Dgeo_1749 | Dgeo_2140 | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase: (9.3e-34) Helix-turn-helix biotin operon repressor region: (3.4e-19); PFAM: biotin protein ligase-like: (5.6e-05) biotin/lipoate A/B protein ligase: (1.8e-16); KEGG: dra:DR2341 birA bifunctional protein, ev=1e-111, 69% identity. | 0.830 |
coaX | Dgeo_2315 | Dgeo_1749 | Dgeo_2315 | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.925 |
coaX | coaD | Dgeo_1749 | Dgeo_0286 | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | Phosphopantetheine adenylyltransferase, CoaD; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.960 |
coaX | hslO | Dgeo_1749 | Dgeo_0553 | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | 0.453 |
coaX | panC | Dgeo_1749 | Dgeo_0670 | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.967 |
coaX | panD | Dgeo_1749 | Dgeo_1422 | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.656 |