STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plsXFatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (346 aa)    
Predicted Functional Partners:
plsY
Protein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
 
  
 0.978
Dgeo_0177
PFAM: protein of unknown function DUF205: (2.4e-10); KEGG: dra:DR2270 hypothetical protein, ev=2e-60, 64% identity; Belongs to the PlsY family.
 
  
 0.948
Dgeo_0434
TIGRFAM: malonyl CoA-acyl carrier protein transacylase: (1.8e-118); PFAM: acyl transferase region: (1.8e-14); KEGG: dra:DR1945 malonyl CoA-acyl carrier protein transacylase, ev=1e-126, 76% identity.
  
  
 0.914
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
  
 0.901
Dgeo_1835
PFAM: protein of unknown function DUF88: (6.5e-80); KEGG: dra:DR1997m hypothetical protein, ev=7e-80, 85% identity.
       0.840
rpmF
TIGRFAM: ribosomal protein L32: (3.4e-34); PFAM: ribosomal L32p protein: (1.5e-31); KEGG: dra:DR2366 50S ribosomal protein L32, ev=2e-28, 91% identity; Belongs to the bacterial ribosomal protein bL32 family.
  
  
 0.825
rpsM
Ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.
   
    0.823
Dgeo_1833
PFAM: MscS Mechanosensitive ion channel: (2.8e-52); KEGG: dra:DR1995 hypothetical protein, ev=1e-154, 65% identity.
       0.820
Dgeo_1836
PFAM: protein of unknown function DUF309: (1.7e-21); KEGG: dra:DR0943 hypothetical protein, ev=5e-34, 66% identity.
       0.798
Dgeo_1837
TIGRFAM: thioredoxin: (3.7e-58); PFAM: Thioredoxin domain: (1.7e-39); KEGG: dra:DR0944 thioredoxin, ev=2e-48, 84% identity; Belongs to the thioredoxin family.
       0.769
Your Current Organism:
Deinococcus geothermalis
NCBI taxonomy Id: 319795
Other names: D. geothermalis DSM 11300, Deinococcus geothermalis AG-3a, Deinococcus geothermalis CIP 105573, Deinococcus geothermalis DSM 11300, Deinococcus geothermalis str. DSM 11300, Deinococcus geothermalis strain DSM 11300
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