node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dgeo_0021 | Dgeo_0823 | Dgeo_0021 | Dgeo_0823 | Cys/Met metabolism PLP-dependent enzyme containing HRDC domain; PFAM: HRDC: (2.5e-18); KEGG: dra:DR2444 nucleic acid-binding protein, putative, HRDC family, ev=1e-141, 52% identity. | SbcC, ATPase involved in DNA repair; PFAM: SMC protein-like: (9.9e-10); KEGG: dra:DR1922 exonuclease SbcC, ev=0.0, 61% identity. | 0.745 |
Dgeo_0021 | polA | Dgeo_0021 | Dgeo_1666 | Cys/Met metabolism PLP-dependent enzyme containing HRDC domain; PFAM: HRDC: (2.5e-18); KEGG: dra:DR2444 nucleic acid-binding protein, putative, HRDC family, ev=1e-141, 52% identity. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.908 |
Dgeo_0021 | recA | Dgeo_0021 | Dgeo_2138 | Cys/Met metabolism PLP-dependent enzyme containing HRDC domain; PFAM: HRDC: (2.5e-18); KEGG: dra:DR2444 nucleic acid-binding protein, putative, HRDC family, ev=1e-141, 52% identity. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.802 |
Dgeo_0021 | topA | Dgeo_0021 | Dgeo_2001 | Cys/Met metabolism PLP-dependent enzyme containing HRDC domain; PFAM: HRDC: (2.5e-18); KEGG: dra:DR2444 nucleic acid-binding protein, putative, HRDC family, ev=1e-141, 52% identity. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.873 |
Dgeo_0165 | dnaX | Dgeo_0165 | Dgeo_2135 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.962 |
Dgeo_0165 | polA | Dgeo_0165 | Dgeo_1666 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.697 |
Dgeo_0165 | recA | Dgeo_0165 | Dgeo_2138 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.476 |
Dgeo_0165 | topA | Dgeo_0165 | Dgeo_2001 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.779 |
Dgeo_0823 | Dgeo_0021 | Dgeo_0823 | Dgeo_0021 | SbcC, ATPase involved in DNA repair; PFAM: SMC protein-like: (9.9e-10); KEGG: dra:DR1922 exonuclease SbcC, ev=0.0, 61% identity. | Cys/Met metabolism PLP-dependent enzyme containing HRDC domain; PFAM: HRDC: (2.5e-18); KEGG: dra:DR2444 nucleic acid-binding protein, putative, HRDC family, ev=1e-141, 52% identity. | 0.745 |
Dgeo_0823 | Dgeo_1226 | Dgeo_0823 | Dgeo_1226 | SbcC, ATPase involved in DNA repair; PFAM: SMC protein-like: (9.9e-10); KEGG: dra:DR1922 exonuclease SbcC, ev=0.0, 61% identity. | HRDC domain protein; PFAM: helicase-like: (4.9e-10) HRDC: (5e-23); KEGG: dra:DR1289 DNA helicase RecQ, ev=1e-31, 76% identity. | 0.745 |
Dgeo_0823 | polA | Dgeo_0823 | Dgeo_1666 | SbcC, ATPase involved in DNA repair; PFAM: SMC protein-like: (9.9e-10); KEGG: dra:DR1922 exonuclease SbcC, ev=0.0, 61% identity. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.968 |
Dgeo_0823 | recA | Dgeo_0823 | Dgeo_2138 | SbcC, ATPase involved in DNA repair; PFAM: SMC protein-like: (9.9e-10); KEGG: dra:DR1922 exonuclease SbcC, ev=0.0, 61% identity. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.752 |
Dgeo_0823 | topA | Dgeo_0823 | Dgeo_2001 | SbcC, ATPase involved in DNA repair; PFAM: SMC protein-like: (9.9e-10); KEGG: dra:DR1922 exonuclease SbcC, ev=0.0, 61% identity. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.782 |
Dgeo_1226 | Dgeo_0823 | Dgeo_1226 | Dgeo_0823 | HRDC domain protein; PFAM: helicase-like: (4.9e-10) HRDC: (5e-23); KEGG: dra:DR1289 DNA helicase RecQ, ev=1e-31, 76% identity. | SbcC, ATPase involved in DNA repair; PFAM: SMC protein-like: (9.9e-10); KEGG: dra:DR1922 exonuclease SbcC, ev=0.0, 61% identity. | 0.745 |
Dgeo_1226 | polA | Dgeo_1226 | Dgeo_1666 | HRDC domain protein; PFAM: helicase-like: (4.9e-10) HRDC: (5e-23); KEGG: dra:DR1289 DNA helicase RecQ, ev=1e-31, 76% identity. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.908 |
Dgeo_1226 | recA | Dgeo_1226 | Dgeo_2138 | HRDC domain protein; PFAM: helicase-like: (4.9e-10) HRDC: (5e-23); KEGG: dra:DR1289 DNA helicase RecQ, ev=1e-31, 76% identity. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.805 |
Dgeo_1226 | topA | Dgeo_1226 | Dgeo_2001 | HRDC domain protein; PFAM: helicase-like: (4.9e-10) HRDC: (5e-23); KEGG: dra:DR1289 DNA helicase RecQ, ev=1e-31, 76% identity. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.873 |
Dgeo_1498 | polA | Dgeo_1498 | Dgeo_1666 | rRNA methyltransferase, sun family protein; PFAM: Fmu (Sun): (9e-14) NusB/RsmB/TIM44: (4.9e-28); KEGG: dra:DR2168 sun protein, putative, ev=1e-161, 72% identity; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.605 |
Dgeo_1498 | recA | Dgeo_1498 | Dgeo_2138 | rRNA methyltransferase, sun family protein; PFAM: Fmu (Sun): (9e-14) NusB/RsmB/TIM44: (4.9e-28); KEGG: dra:DR2168 sun protein, putative, ev=1e-161, 72% identity; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.500 |
Dgeo_1498 | secF | Dgeo_1498 | Dgeo_1239 | rRNA methyltransferase, sun family protein; PFAM: Fmu (Sun): (9e-14) NusB/RsmB/TIM44: (4.9e-28); KEGG: dra:DR2168 sun protein, putative, ev=1e-161, 72% identity; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.685 |