STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dgeo_2242TIGRFAM: UDP-glucose 4-epimerase: (1.3e-209); PFAM: NAD-dependent epimerase/dehydratase: (7.7e-77) 3-beta hydroxysteroid dehydrogenase/isomerase: (1.1e-09) polysaccharide biosynthesis protein CapD: (0.00025) dTDP-4-dehydrorhamnose reductase: (1.5e-07) Male sterility-like: (1.4e-06); KEGG: dra:DR2202 UDP-glucose 4-epimerase, ev=1e-155, 80% identity; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (334 aa)    
Predicted Functional Partners:
Dgeo_2243
Transcriptional regulator, LacI family; PFAM: regulatory protein, LacI: (1.4e-05) periplasmic binding protein/LacI transcriptional regulator: (3.1e-09); KEGG: dra:DR2501 transcriptional regulator, sugar-binding, putative, ev=1e-96, 59% identity.
 
 
 0.887
Dgeo_0343
Undecaprenyl-phosphate galactosephosphotransferase; PFAM: sugar transferase: (1.2e-86); KEGG: dra:DRA0034 UDP-galactose-lipid carrier transferase, ev=1e-175, 64% identity.
 
   
 0.759
Dgeo_2008
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
 
   
 0.654
Dgeo_2244
PFAM: major facilitator superfamily MFS_1: (1.4e-20); KEGG: dra:DR2502 transport protein, putative, ev=1e-146, 71% identity.
  
  
 0.530
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
   
 
 0.519
Dgeo_0321
PFAM: mannose-6-phosphate isomerase, type I: (1.3e-09); KEGG: dra:DRA0048 mannose-6-phosphate isomerase, putative, ev=7e-94, 58% identity.
 
   
 0.501
glmS
Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
  
 0.464
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
 
  
 0.442
Dgeo_0752
Transcriptional regulator, LacI family; PFAM: regulatory protein, LacI: (7.6e-11) periplasmic binding protein/LacI transcriptional regulator: (6e-05); KEGG: sma:SAV554 putative LacI-family transcriptional regulator, ev=3e-33, 35% identity.
 
 
 0.437
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.
  
 
 0.434
Your Current Organism:
Deinococcus geothermalis
NCBI taxonomy Id: 319795
Other names: D. geothermalis DSM 11300, Deinococcus geothermalis AG-3a, Deinococcus geothermalis CIP 105573, Deinococcus geothermalis DSM 11300, Deinococcus geothermalis str. DSM 11300, Deinococcus geothermalis strain DSM 11300
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