STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFA61964.1Hypothetical protein. (86 aa)    
Predicted Functional Partners:
SFA49923.1
Cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
  
    0.925
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
   
  
 0.736
SFA64512.1
DNA polymerase V; Belongs to the peptidase S24 family.
   
  
 0.736
SFA66551.1
DNA polymerase V; Belongs to the peptidase S24 family.
   
  
 0.736
SFA60798.1
DNA repair protein RecN (Recombination protein N); May be involved in recombinational repair of damaged DNA.
   
  
 0.694
SFA61482.1
N-acetylglucosaminyl deacetylase, LmbE family.
  
     0.688
SFA38994.1
Hypothetical protein.
  
     0.686
SFA64552.1
Outer membrane protein assembly factor BamC.
  
     0.660
SFA58122.1
Hypothetical protein.
  
     0.659
SFA57606.1
SMI1-KNR4 cell-wall.
  
     0.656
Your Current Organism:
Pseudomonas otitidis
NCBI taxonomy Id: 319939
Other names: DSM 17224, P. otitidis, Pseudomonas otitidis Clark et al. 2006, strain MCC10330
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.