STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFA64285.1Cobalt uptake substrate-specific transmembrane region. (227 aa)    
Predicted Functional Partners:
SFA65825.1
Cobalt-precorrin 5A hydrolase / precorrin-3B C17-methyltransferase.
 
  
 0.942
SFA65835.1
precorrin-6A/cobalt-precorrin-6A reductase.
 
  
 0.932
SFA65863.1
Cobalt-precorrin 5A hydrolase/cobalt-precorrin 5A hydrolase / precorrin-3B C17-methyltransferase.
  
  
 0.930
SFA65833.1
precorrin-6Y C5,15-methyltransferase (decarboxylating).
 
 
 0.809
SFA65829.1
precorrin-8X methylmutase.
 
 
 0.726
SFA65827.1
Precorrin-2/cobalt-factor-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A.
 
  
 0.593
cysG
uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
  
 0.554
SFA65974.1
precorrin-6A synthase (deacetylating).
  
  
 0.525
cobB-2
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
   
 0.503
SFA65865.1
Precorrin-4/cobalt-precorrin-4 C11-methyltransferase.
 
  
 0.478
Your Current Organism:
Pseudomonas otitidis
NCBI taxonomy Id: 319939
Other names: DSM 17224, P. otitidis, Pseudomonas otitidis Clark et al. 2006, strain MCC10330
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