STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OJG35061.1Hypothetical protein. (395 aa)    
Predicted Functional Partners:
OJG36921.1
Methylase; Belongs to the methyltransferase superfamily.
  
 0.891
OJG35060.1
3-dehydroquinate dehydratase, type I.
       0.867
OJG35062.1
Sulfatase.
       0.790
aroD
3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
       0.607
OJG36576.1
dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
    
  0.516
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
  0.506
folD
FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
  0.501
OJG36525.1
Pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family.
 
 
 
 0.485
OJG37235.1
16S rRNA pseudouridylate synthase A; Belongs to the pseudouridine synthase RsuA family.
 
 
 
 0.483
OJG35785.1
FolC protein; Belongs to the folylpolyglutamate synthase family.
  
 
  0.475
Your Current Organism:
Enterococcus devriesei
NCBI taxonomy Id: 319970
Other names: CCM 7299, CCUG 37865, DSM 22802, E. devriesei, Enterococcus devriesei Svec et al. 2005, LMG 14595, LMG:14595
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.