Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OLU06587.12-methylcitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)    
Predicted Functional Partners:
OLU06586.1
2-methylcitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
 
 0.994
prpF
Putative methylaconitate Delta-isomerase PrpF; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.951
acnB
Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family.
   
 0.938
acnA4
Fe/S-dependent 2-methylisocitrate dehydratase AcnD; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.914
acnA-3
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.914
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
  
 0.868
OLU09825.1
Carboxyvinyl-carboxyphosphonate phosphorylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.835
OLU08987.1
Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.824
GltA
Citrate (Si)-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
  
 
 0.754
BVK87_21935
Hypothetical protein; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.694
Your Current Organism:
Achromobacter denitrificans
NCBI taxonomy Id: 32002
Other names: A. denitrificans, ATCC 15173, Achromobacter xylosoxidans subsp. denitrificans, Alcaligenes denitrificans, Alcaligenes denitrificans denitrificans, Alcaligenes denitrificans subsp. denitrificans, Alcaligenes xylosoxidans subsp. denitrificans, Alcaligenes xylosoxydans denitrificans, CCUG 407, CIP 77.15, DSM 30026, IFO 15125, JCM 5490, JCM 9657, NBRC 15125, NCTC 8582
Server load: low (22%) [HD]