STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proAUnannotated protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (407 aa)    
Predicted Functional Partners:
proB
Unannotated protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.999
putA
Unannotated protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
  
 
 0.936
gltB
Unannotated protein.
    
 0.886
atpA
Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
 
    
 0.866
glnA
Unannotated protein.
     
 0.865
purQ
Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...]
   
 
 0.839
gdhA
Unannotated protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.823
gltD
Unannotated protein.
    
 0.807
proC
Unannotated protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.784
por
Unannotated protein.
   
   0.752
Your Current Organism:
Campylobacter fetus venerealis
NCBI taxonomy Id: 32020
Other names: ATCC 19438, C. fetus subsp. venerealis, CCUG 33899, CCUG 538, CIP 68.29, Campylobacter fetus subsp. venerealis, Campylobacter fetus subsp. venereus, DSM 18826, JCM 2528, LMG 6443, LMG:6443, NCTC 10354, Vibrio fetus subsp. venerealis, Vibrio foetus venerealis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.