STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemCUnannotated protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (317 aa)    
Predicted Functional Partners:
hemA
Unannotated protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
 0.995
hemE_2
Unannotated protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 0.989
hemB
Unannotated protein; Belongs to the ALAD family.
 
 0.987
hemD
Unannotated protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
 0.973
hemL_2
Unannotated protein.
 
  
 0.881
ispB
Unannotated protein; Belongs to the FPP/GGPP synthase family.
  
  
 0.869
GCA_000788295_00208
Unannotated protein.
       0.800
proS
Unannotated protein; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacyl [...]
       0.800
GCA_000788295_00212
Unannotated protein.
       0.800
hemL_1
Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.754
Your Current Organism:
Campylobacter sputorum
NCBI taxonomy Id: 32024
Other names: C. sputorum biovar sputorum, Campylobacter sputorum biovar sputorum, Campylobacter sputorum bv. sputorum, Campylobacter sputorum sputorum, Campylobacter sputorum subsp. sputorum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.