STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMF_002Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.582(Affirmative). (200 aa)    
Predicted Functional Partners:
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (purE); Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
       0.831
tdpX1
Thioredoxin peroxidase 1 (tdpX1); Psort: bacterial cytoplasm --- Certainty= 0.065(Affirmative); COG0450 AhpC peroxiredoxin.
  
 0.794
AMF_1031
Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.501(Affirmative).
   
 0.747
pdhD
Dihydrolipoamide dehydrogenase (pdhD); Psort: bacterial inner membrane --- Certainty= 0.117(Affirmative).
   
  0.689
lpdA
Dihydrolipoamide dehydrogenase (lpdA); Psort: bacterial membrane --- Certainty= 0.512(Affirmative); COG1249 Lpd dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes.
   
  0.689
dsbD
C-type cytochrome biogenesis protein (dsbD); Psort: bacterial inner membrane --- Certainty= 0.427(Affirmative); COG0526 TrxA thiol-disulfide isomerase and thioredoxins.
  
 
 0.685
hscA
Heat shock protein (hscA); Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
   
  0.645
dnaK
DNAK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
  0.645
AMF_867
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.582(Affirmative).
    
  0.598
dnaJ
DNAJ protein (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...]
    
  0.598
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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