STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rodARod shape determining protein (rodA); Psort: bacterial inner membrane --- Certainty= 0.429(Affirmative); COG0772 FtsW bacterial cell division membrane protein; Belongs to the SEDS family. (357 aa)    
Predicted Functional Partners:
pbpA1
Penicillin-binding protein (pbpA1); Psort: bacterial inner membrane --- Certainty= 0.348(Affirmative); COG0768 FtsI cell division protein FtsI/penicillin-binding protein 2.
 
 0.987
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
 0.941
pbpA2
Penicillin-binding protein (pbpA2); Psort: bacterial inner membrane --- Certainty= 0.516(Affirmative); COG0768 FtsI cell division protein FtsI/penicillin-binding protein 2.
 
 0.912
mreB
Rod shape-determining protein (mreB); Psort: bacterial inner membrane --- Certainty= 0.270(Affirmative); COG1077 MreB HSP70 class molecular chaperones involved in cell morphogenesis.
 
 
 0.883
ftsQ
Cell division protein (ftsQ); Psort: bacterial cytoplasm --- Certainty= 0.174(Affirmative); COG1589 FtsQ cell division septal protein.
  
 
 0.849
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase (murA); Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
 
  
 0.838
murC
UDP-N-acetylmuramate-alanine ligase (murC); Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.827
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase (murD); Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
 0.798
mraY1
Phospho-n-acetylmuramoyl-pentapeptide- transferase (mraY1); First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.745
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase (murF); Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
 
 0.714
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.