Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMF_007Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.277(Affirmative); COG0789 SoxR Predicted transcriptional regulators. (124 aa)    
Predicted Functional Partners:
ihfA
Presumptive integration host factor alpha-subunit (ihfA); This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
  
  
 0.963
rpoB
RNA polymerase beta subunit (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.818
rpsG
30S ribosomal protein S7 (rpsG); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
    0.795
rpoC
DNA-directed RNA polymerase beta' chain (rpoC); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.777
rpoA
DNA-directed RNA polymerase alpha chain (rpoA); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.772
rplU
50S ribosomal protein L21 (rplU); This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
    0.771
rpoZ
DNA-directed RNA polymerase omega subunit (rpoZ); Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.769
rpoD
RNA polymerase sigma factor (rpoD); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.705
rpoH
RNA polymerase sigma-32 factor (rpoH); Psort: bacterial cytoplasm --- Certainty= 0.052(Affirmative); COG0568 RpoD DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); Belongs to the sigma-70 factor family.
  
 
 0.705
glnA
Glutamine synthetase (glnA); Psort: bacterial cytoplasm --- Certainty= 0.125(Affirmative); COG0174 GlnA glutamine synthase; Belongs to the glutamine synthetase family.
  
 
 0.687
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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