STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xerDTyrosine recombinase (xerD); Psort: bacterial inner membrane --- Certainty= 0.285(Affirmative); COG0582 XerC integrase; Belongs to the 'phage' integrase family. (312 aa)    
Predicted Functional Partners:
AMF_017
Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.270(Affirmative).
       0.773
rnhA
Ribonuclease H (rnhA); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
      
 0.665
rnhB
Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
     
 0.661
guaB
Inosine monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.660
purL
Phosphoribosylformylglycinamidine synthase (PurL); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to ass [...]
      
 0.648
fpbA
Iron binding protein FbpA precursor (fpbA); Psort: bacterial inner membrane --- Certainty= 0.459(Affirmative).
      
 0.623
dnaE
DNA polymerase III, alpha subunit (dnaE); Psort: bacterial inner membrane --- Certainty= 0.113(Affirmative); COG0587 DnaE DNA polymerase III alpha subunit.
   
  
 0.591
comF
Competence protein F (comF); Psort: bacterial inner membrane --- Certainty= 0.185(Affirmative); COG1040 ComFC Predicted amidophosphoribosyltransferases.
   
    0.578
guaA
GMP synthase (glutamine-hydrolyzing) (guaA); Catalyzes the synthesis of GMP from XMP.
     
 0.557
pyrG
CTP synthase (pyrG); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
    0.529
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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