STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phnLATP transporter ATP-binding protein (phnL); Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (224 aa)    
Predicted Functional Partners:
lolE
Lipoprotein-releasing system transmembrane protein (lolE); Psort: bacterial inner membrane --- Certainty= 0.605(Affirmative).
 
 0.999
AMF_806
Conserved hypothetical protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
   
 
 0.931
hlyD
Putative secretion protein hlyD; Psort: bacterial cytoplasm --- Certainty= 0.244(Affirmative); COG0845 AcrA Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.883
tolC
Outer membrane protein (tolC); Psort: bacterial inner membrane --- Certainty= 0.295(Affirmative); COG1538 TolC outer membrane protein.
   
 
 0.715
aprE
Alkaline protease secretion protein (aprE); Psort: bacterial inner membrane --- Certainty= 0.569(Affirmative); COG1404 aprE subtilisin-like serine proteases.
  
 
 0.686
pstC
ABC-type phosphate transport system, permease component (pstC); Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
      
 0.678
ksgA
Dimethyladenosine transferase (ksgA); Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
 
 
 0.593
pstS
Phosphate ABC transporter, periplasmic phosphate-binding protein; Psort: bacterial outer membrane --- Certainty= 0.239(Affirmative) bacterial periplasmic space --- Certainty= 0.239(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.984 Max cleavage site probability: 0.934 between pos. 20 and 21; COG0226 ABC-type phosphate transport system, periplasmic component.
     
 0.553
maeB
Malate dehydrogenase and phosphate acetyltransferase (maeB); Psort: bacterial inner membrane --- Certainty= 0.140(Affirmative); COG0039 Mdh malate/lactate dehydrogenases.
       0.539
msbA2
ABC efflux transporter (msbA2); Psort: bacterial inner membrane --- Certainty= 0.397(Affirmative); COG1132 MdlB ABC-type multidrug/protein/lipid transport system, ATPase component.
   
0.526
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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