STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msp4Major surface protein 4 (msp4); Member of msp2 superfamily; psort: bacterial cytoplasm --- Certainty= 0.211(Affirmative) signalP: Prediction: Signal peptide Signal peptide probability: 1.000 Max cleavage site probability: 0.933 between pos. 29 and 30. (282 aa)    
Predicted Functional Partners:
msp5
Major surface protein 5 (MSP5); Psort: bacterial inner membrane --- Certainty= 0.391(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.837 Max cleavage site probability: 0.403 between pos. 26 and 27.
      
 0.718
gltA
Citrate synthase (gltA); Psort: bacterial cytoplasm --- Certainty= 0.043(Affirmative); COG0372 GltA citrate synthase.
   
  
 0.699
groEL
60 kD chaperonin (groEL); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
      
 0.695
msp1a
Major surface protein 1a (MSP1A); Member of msp1 superfamily; psort: bacterial inner membrane --- Certainty= 0.567(Affirmative).
      
 0.690
ankA
Ankyrin (ankA); Psort: bacterial cytoplasm --- Certainty= 0.332(Affirmative); COG0666 Arp ankyrin repeat proteins.
      
 0.659
dnaK
DNAK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
      
 0.552
rpmF
Large subunit ribosomal protein L32 (rpmF); Psort: bacterial cytoplasm --- Certainty= 0.081(Affirmative); COG0333 RpmF ribosomal protein L32.
    
 
 0.536
msp2
Major surface protein 2 (MSP2); Member of msp2 superfamily; psort: bacterial outer membrane --- Certainty= 0.934(Affirmative).
      
0.505
msp3
Major surface protein 3 (MSP3); Member of msp2 superfamily; psort: bacterial periplasmic space --- Certainty= 0.930(Affirmative).
      
0.503
typA
GTP-binding protein TypA (typA); Psort: bacterial inner membrane --- Certainty= 0.157(Affirmative); COG1217 TypA predicted membrane GTPase involved in stress response.
      
 0.495
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.