STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase E1 component, alpha subunit precursor (pdhA); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (372 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 beta subunit precursor (pdhB); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
pdhC
Dihydrolipoamide acetyltransferase component (pdhC); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.999
pdhD
Dihydrolipoamide dehydrogenase (pdhD); Psort: bacterial inner membrane --- Certainty= 0.117(Affirmative).
  
 
 0.994
lpdA
Dihydrolipoamide dehydrogenase (lpdA); Psort: bacterial membrane --- Certainty= 0.512(Affirmative); COG1249 Lpd dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes.
  
 
 0.994
sucB
Dihydrolipoamide acetyltransferase component (sucB); Psort: bacterial inner membrane --- Certainty= 0.238(Affirmative); COG0508 AceF dihydrolipoamide acyltransferases.
 
 0.981
maeB
Malate dehydrogenase and phosphate acetyltransferase (maeB); Psort: bacterial inner membrane --- Certainty= 0.140(Affirmative); COG0039 Mdh malate/lactate dehydrogenases.
  
 
 0.971
sucA
2-oxoglutarate dehydrogenase E1 component (sucA); Psort: bacterial cytoplasm --- Certainty= 0.276(Affirmative); COG0567 SucA pyruvate and 2-oxoglutarate dehydrogenases, E1 component.
     
 0.923
ppdK
Pyruvate, phosphate dikinase precursor (ppdK); Psort: bacterial cytoplasm --- Certainty= 0.272(Affirmative); COG0574 PpsA phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
    
 0.916
tktA
Transketolase (TktA); Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.872
prsA
Ribose-phosphate pyrophosphokinase (prsA); Psort: bacterial periplasmic space --- Certainty= 0.933(Affirmative); COG0462 PrsA phosphoribosylpyrophosphate synthetase.
    
 0.860
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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