STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnhARibonuclease H (rnhA); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (171 aa)    
Predicted Functional Partners:
rnhB
Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
 
 0.931
dnaQ
DNA polymerase III, epsilon chain (dnaQ); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
 
  
 0.926
ssb
Single-strand binding protein (ssb); Psort: bacterial cytoplasm --- Certainty= 0.082(Affirmative); COG0629 Ssb single-stranded DNA-binding protein.
   
 
 0.827
AMF_093
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.317(Affirmative).
       0.806
guaB
Inosine monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.698
xerD
Tyrosine recombinase (xerD); Psort: bacterial inner membrane --- Certainty= 0.285(Affirmative); COG0582 XerC integrase; Belongs to the 'phage' integrase family.
      
 0.665
topA
DNA topoisomerase I (topA); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...]
    
 
 0.664
polA
DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.644
cdsA
Phosphatidate cytidylyltransferase (cdsA); COG0575 CdsA CDP-diglyceride synthetase.
  
    0.632
fpbA
Iron binding protein FbpA precursor (fpbA); Psort: bacterial inner membrane --- Certainty= 0.459(Affirmative).
      
 0.630
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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