rnhA protein (Anaplasma marginale) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

rnhA

Ribonuclease H (rnhA); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (171 aa)

Predicted Functional Partners:

dnaQ

0.933

rnhB

0.912

ssb

0.815

AMF_093

0.782

polA

0.658

cdsA

0.636

pyrH

0.626

rrf

0.623

uppS

0.620

mfd

0.619

Your Current Organism:

Anaplasma marginale

NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMF_093	cdsA	AMF_093	AMF_097	Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.317(Affirmative).	Phosphatidate cytidylyltransferase (cdsA); COG0575 CdsA CDP-diglyceride synthetase.	0.629
AMF_093	mfd	AMF_093	AMF_091	Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.317(Affirmative).	Transcription repair coupling factor (mfd); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	0.551
AMF_093	pyrH	AMF_093	AMF_094	Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.317(Affirmative).	Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.	0.647
AMF_093	rnhA	AMF_093	AMF_092	Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.317(Affirmative).	Ribonuclease H (rnhA); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.782
AMF_093	rrf	AMF_093	AMF_095	Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.317(Affirmative).	Ribosome recycling factor (rrf); Psort: bacterial cytoplasm --- Certainty= 0.230(Affirmative); COG0233 Frr Ribosome recycling factor.	0.647
AMF_093	uppS	AMF_093	AMF_096	Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.317(Affirmative).	Undecaprenyl diphosphate synthase (uppS); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.	0.629
cdsA	AMF_093	AMF_097	AMF_093	Phosphatidate cytidylyltransferase (cdsA); COG0575 CdsA CDP-diglyceride synthetase.	Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.317(Affirmative).	0.629
cdsA	mfd	AMF_097	AMF_091	Phosphatidate cytidylyltransferase (cdsA); COG0575 CdsA CDP-diglyceride synthetase.	Transcription repair coupling factor (mfd); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	0.457
cdsA	pyrH	AMF_097	AMF_094	Phosphatidate cytidylyltransferase (cdsA); COG0575 CdsA CDP-diglyceride synthetase.	Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.	0.901
cdsA	rnhA	AMF_097	AMF_092	Phosphatidate cytidylyltransferase (cdsA); COG0575 CdsA CDP-diglyceride synthetase.	Ribonuclease H (rnhA); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.636
cdsA	rrf	AMF_097	AMF_095	Phosphatidate cytidylyltransferase (cdsA); COG0575 CdsA CDP-diglyceride synthetase.	Ribosome recycling factor (rrf); Psort: bacterial cytoplasm --- Certainty= 0.230(Affirmative); COG0233 Frr Ribosome recycling factor.	0.847
cdsA	uppS	AMF_097	AMF_096	Phosphatidate cytidylyltransferase (cdsA); COG0575 CdsA CDP-diglyceride synthetase.	Undecaprenyl diphosphate synthase (uppS); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.	0.989
dnaQ	polA	AMF_467	AMF_914	DNA polymerase III, epsilon chain (dnaQ); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.649
dnaQ	rnhA	AMF_467	AMF_092	DNA polymerase III, epsilon chain (dnaQ); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Ribonuclease H (rnhA); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.933
mfd	AMF_093	AMF_091	AMF_093	Transcription repair coupling factor (mfd); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.317(Affirmative).	0.551
mfd	cdsA	AMF_091	AMF_097	Transcription repair coupling factor (mfd); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	Phosphatidate cytidylyltransferase (cdsA); COG0575 CdsA CDP-diglyceride synthetase.	0.457
mfd	polA	AMF_091	AMF_914	Transcription repair coupling factor (mfd); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.474
mfd	pyrH	AMF_091	AMF_094	Transcription repair coupling factor (mfd); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.	0.467
mfd	rnhA	AMF_091	AMF_092	Transcription repair coupling factor (mfd); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	Ribonuclease H (rnhA); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.619
mfd	rrf	AMF_091	AMF_095	Transcription repair coupling factor (mfd); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	Ribosome recycling factor (rrf); Psort: bacterial cytoplasm --- Certainty= 0.230(Affirmative); COG0233 Frr Ribosome recycling factor.	0.457