| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF_093 | cdsA | AMF_093 | AMF_097 | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.317(Affirmative). | Phosphatidate cytidylyltransferase (cdsA); COG0575 CdsA CDP-diglyceride synthetase. | 0.629 |
| AMF_093 | rnhA | AMF_093 | AMF_092 | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.317(Affirmative). | Ribonuclease H (rnhA); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.806 |
| cdsA | AMF_093 | AMF_097 | AMF_093 | Phosphatidate cytidylyltransferase (cdsA); COG0575 CdsA CDP-diglyceride synthetase. | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.317(Affirmative). | 0.629 |
| cdsA | rnhA | AMF_097 | AMF_092 | Phosphatidate cytidylyltransferase (cdsA); COG0575 CdsA CDP-diglyceride synthetase. | Ribonuclease H (rnhA); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.632 |
| dnaQ | polA | AMF_467 | AMF_914 | DNA polymerase III, epsilon chain (dnaQ); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.633 |
| dnaQ | rnhA | AMF_467 | AMF_092 | DNA polymerase III, epsilon chain (dnaQ); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | Ribonuclease H (rnhA); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.926 |
| dnaQ | ssb | AMF_467 | AMF_310 | DNA polymerase III, epsilon chain (dnaQ); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | Single-strand binding protein (ssb); Psort: bacterial cytoplasm --- Certainty= 0.082(Affirmative); COG0629 Ssb single-stranded DNA-binding protein. | 0.445 |
| dnaQ | topA | AMF_467 | AMF_373 | DNA polymerase III, epsilon chain (dnaQ); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | DNA topoisomerase I (topA); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...] | 0.498 |
| fpbA | guaB | AMF_050 | AMF_073 | Iron binding protein FbpA precursor (fpbA); Psort: bacterial inner membrane --- Certainty= 0.459(Affirmative). | Inosine monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.576 |
| fpbA | rnhA | AMF_050 | AMF_092 | Iron binding protein FbpA precursor (fpbA); Psort: bacterial inner membrane --- Certainty= 0.459(Affirmative). | Ribonuclease H (rnhA); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.630 |
| fpbA | rnhB | AMF_050 | AMF_196 | Iron binding protein FbpA precursor (fpbA); Psort: bacterial inner membrane --- Certainty= 0.459(Affirmative). | Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.560 |
| fpbA | xerD | AMF_050 | AMF_018 | Iron binding protein FbpA precursor (fpbA); Psort: bacterial inner membrane --- Certainty= 0.459(Affirmative). | Tyrosine recombinase (xerD); Psort: bacterial inner membrane --- Certainty= 0.285(Affirmative); COG0582 XerC integrase; Belongs to the 'phage' integrase family. | 0.623 |
| guaB | fpbA | AMF_073 | AMF_050 | Inosine monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Iron binding protein FbpA precursor (fpbA); Psort: bacterial inner membrane --- Certainty= 0.459(Affirmative). | 0.576 |
| guaB | polA | AMF_073 | AMF_914 | Inosine monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.566 |
| guaB | rnhA | AMF_073 | AMF_092 | Inosine monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Ribonuclease H (rnhA); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.698 |
| guaB | rnhB | AMF_073 | AMF_196 | Inosine monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.748 |
| guaB | xerD | AMF_073 | AMF_018 | Inosine monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Tyrosine recombinase (xerD); Psort: bacterial inner membrane --- Certainty= 0.285(Affirmative); COG0582 XerC integrase; Belongs to the 'phage' integrase family. | 0.660 |
| polA | dnaQ | AMF_914 | AMF_467 | DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA polymerase III, epsilon chain (dnaQ); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.633 |
| polA | guaB | AMF_914 | AMF_073 | DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Inosine monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.566 |
| polA | rnhA | AMF_914 | AMF_092 | DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Ribonuclease H (rnhA); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.644 |