STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
dapFDiaminopimelate epimerase (dapF); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (277 aa)    
Predicted Functional Partners:
dapE
Succinyl-diaminopimelate desuccinylase (dapE); Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
    
 0.972
murE
UDP-N-acetylmuramoylalanyl-D-glutamate-- 2,6-diaminopimelate ligase (murE); Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
    
 0.971
carB
Carbamyl-phosphate synthase, large subunit (carB); Psort: bacterial inner membrane --- Certainty= 0.157(Affirmative); COG0458 CarB carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family.
      0.882
asd
Aspartate-semialdehyde dehydrogenase (asd); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
  
 0.795
AMF_1003
Hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.932(Affirmative).
       0.762
dapD
2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase (dapD); Psort: bacterial inner membrane --- Certainty= 0.106(Affirmative); COG2171 DapD tetrahydrodipicolinate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.
  
  
 0.743
argD
Acetylornithine aminotransferase (argD); Psort: bacterial cytoplasm --- Certainty= 0.069(Affirmative); COG0160 ArgD PLP-dependent aminotransferases.
 
 
 0.696
ddlB
D-alanine--D-alanine ligase (ddlB); Cell wall formation.
  
  
 0.692
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase (murF); Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
     
 0.684
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase (murD); Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
      
 0.668
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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