STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgkPhosphoglycerate kinase (pgk); Psort: bacterial inner membrane --- Certainty= 0.111(Affirmative); COG0126 Pgk 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (398 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase (tpiA); Psort: bacterial inner membrane --- Certainty= 0.251(Affirmative); COG0149 TpiA triosephosphate isomerase.
 
 0.999
gapA
Psort: bacterial cytoplasm --- Certainty= 0.128(Affirmative); COG0057 GapA glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase.
 
 0.999
eno
Enolase 1 (2-phosphoglycerate dehydratase 1) (eno); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.996
yibO
2,3-bisphosphoglycerate-independent phosphoglycerol mutase (yibO); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 
 0.986
tktA
Transketolase (TktA); Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.766
AMF_1023
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.340(Affirmative); COG0526 Thiol-disulfide isomerase and thioredoxins.
      0.757
metK
S-adenosylmethionine synthetase (metK); Psort: bacterial inner membrane --- Certainty= 0.121(Affirmative); COG0192 MetK S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family.
 
 
 0.744
maeB
Malate dehydrogenase and phosphate acetyltransferase (maeB); Psort: bacterial inner membrane --- Certainty= 0.140(Affirmative); COG0039 Mdh malate/lactate dehydrogenases.
  
 
 0.703
tsf
Translation elongation factor EF-Ts (tsf); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
  
  
 0.698
rplB
50S ribosomal protein L2 (rplB); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
 
 0.694
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.