Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pgkPhosphoglycerate kinase (pgk); Psort: bacterial inner membrane --- Certainty= 0.111(Affirmative); COG0126 Pgk 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (398 aa)    
Predicted Functional Partners:
gapA
Psort: bacterial cytoplasm --- Certainty= 0.128(Affirmative); COG0057 GapA glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase.
 
 0.999
tpiA
Triosephosphate isomerase (tpiA); Psort: bacterial inner membrane --- Certainty= 0.251(Affirmative); COG0149 TpiA triosephosphate isomerase.
 
 0.998
eno
Enolase 1 (2-phosphoglycerate dehydratase 1) (eno); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.989
yibO
2,3-bisphosphoglycerate-independent phosphoglycerol mutase (yibO); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 
 0.978
tktA
Transketolase (TktA); Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.888
ppdK
Pyruvate, phosphate dikinase precursor (ppdK); Psort: bacterial cytoplasm --- Certainty= 0.272(Affirmative); COG0574 PpsA phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
    
 0.880
atpD
ATP synthase beta chain (atpD); Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
  
 
 0.873
rplB
50S ribosomal protein L2 (rplB); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
 
 0.802
rpsS
30S ribosomal protein S19 (rpsS); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
 
 0.799
rplC
50S ribosomal protein L3 (rplC); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.776
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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