STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsbADisulfide oxidoreductase; Psort: bacterial inner membrane --- Certainty= 0.533(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.922 Max cleavage site probability: 0.842 between pos. 21 and 22; COG0526 TrxA Thiol-disulfide isomerase and thioredoxins. (251 aa)    
Predicted Functional Partners:
dsbD
C-type cytochrome biogenesis protein (dsbD); Psort: bacterial inner membrane --- Certainty= 0.427(Affirmative); COG0526 TrxA thiol-disulfide isomerase and thioredoxins.
 
 
 0.962
AMF_083
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.922(Affirmative); COG1651 Protein-disulfide isomerase.
  
     0.675
groEL
60 kD chaperonin (groEL); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
    
 
 0.659
AMF_256
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.164(Affirmative); COG1495 Disulfide bond formation protein DsbB.
  
 
 0.620
polA
DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.567
msp5
Major surface protein 5 (MSP5); Psort: bacterial inner membrane --- Certainty= 0.391(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.837 Max cleavage site probability: 0.403 between pos. 26 and 27.
  
  
 0.557
dsbE
Thiol:disulfide interchange protein (dsbE); Psort: bacterial inner membrane --- Certainty= 0.414(Affirmative); COG0526 TrxA Thiol-disulfide isomerase and thioredoxins.
  
 
 0.450
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.