Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dsbADisulfide oxidoreductase; Psort: bacterial inner membrane --- Certainty= 0.533(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.922 Max cleavage site probability: 0.842 between pos. 21 and 22; COG0526 TrxA Thiol-disulfide isomerase and thioredoxins. (251 aa)    
Predicted Functional Partners:
dsbD
C-type cytochrome biogenesis protein (dsbD); Psort: bacterial inner membrane --- Certainty= 0.427(Affirmative); COG0526 TrxA thiol-disulfide isomerase and thioredoxins.
 
 
 0.907
AMF_256
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.164(Affirmative); COG1495 Disulfide bond formation protein DsbB.
  
 
 0.698
AMF_083
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.922(Affirmative); COG1651 Protein-disulfide isomerase.
  
     0.675
polA
DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.581
groEL
60 kD chaperonin (groEL); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
    
 
 0.505
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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