STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
comFCompetence protein F (comF); Psort: bacterial inner membrane --- Certainty= 0.185(Affirmative); COG1040 ComFC Predicted amidophosphoribosyltransferases. (249 aa)    
Predicted Functional Partners:
smf
DNA processing protein, chain A dprA (smf); Psort: bacterial cytoplasm --- Certainty= 0.158(Affirmative); COG0758 Smf predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.
 
 
 0.870
AMF_669
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.535(Affirmative); COG0658 Predicted multitransmembrane, metal-binding protein.
 
  
 0.845
dapE
Succinyl-diaminopimelate desuccinylase (dapE); Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
       0.817
radC
DNA repair protein (radC); Psort: bacterial cytoplasm --- Certainty= 0.267(Affirmative); COG2003 RadC DNA repair proteins; Belongs to the UPF0758 family.
  
    0.713
ispB
Octaprenyl-diphosphate synthase (ispB); Psort: bacterial inner membrane --- Certainty= 0.181(Affirmative); COG0142 IspA geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
   
  
 0.690
AMF_468
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.102(Affirmative); COG0606 Predicted ATPase with chaperone activity.
 
  
 0.678
mutL
DNA mismatch repair protein (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
  
 0.655
xerD
Tyrosine recombinase (xerD); Psort: bacterial inner membrane --- Certainty= 0.285(Affirmative); COG0582 XerC integrase; Belongs to the 'phage' integrase family.
   
    0.578
xerC
Integrase/recombinase ripx (xerC); Psort: bacterial cytoplasm --- Certainty= 0.189(Affirmative); COG0582 XerC integrase; Belongs to the 'phage' integrase family.
   
    0.578
kefB
Glutathione-regulated potassium-efflux system protein KEFB (kefB); Psort: bacterial inner membrane --- Certainty= 0.637(Affirmative); COG0475 KefB Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
       0.566
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.