Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMF_1024Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.401(Affirmative); COG1981 Predicted membrane protein. (148 aa)    
Predicted Functional Partners:
hemH
Ferrochelatase (hemH); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
    
 0.950
hemF
Coproporphyrinogen III oxidase (hemF); Psort: bacterial cytoplasm --- Certainty= 0.612(Affirmative); COG0408 HemF coproporphyrinogen III oxidase.
 
  
 0.943
kefB
Glutathione-regulated potassium-efflux system protein KEFB (kefB); Psort: bacterial inner membrane --- Certainty= 0.637(Affirmative); COG0475 KefB Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
       0.585
pdhB
Pyruvate dehydrogenase E1 beta subunit precursor (pdhB); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
       0.494
AMF_1023
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.340(Affirmative); COG0526 Thiol-disulfide isomerase and thioredoxins.
  
    0.462
hemE
Uroporphyrinogen decarboxylase (hemE); Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
   
 0.459
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.