Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
coxWCytochrome C oxidase assembly protein (coxW); Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. (341 aa)    
Predicted Functional Partners:
ctaB
Cytochrome c oxidase assembly factor (ctaB); Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
  
 0.990
cox11
Cytochrome c oxidase assembly protein (cox11); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family.
 
 0.987
surf1
Surfeit locus protein 1 (surf1); Psort: bacterial inner membrane --- Certainty= 0.501(Affirmative); COG3346 - uncharacterized conserved protein.
 
 0.977
msp5
Major surface protein 5 (MSP5); Psort: bacterial inner membrane --- Certainty= 0.391(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.837 Max cleavage site probability: 0.403 between pos. 26 and 27.
 
 0.920
adx1
Ferredoxin [2Fe-2S] adrenodoxin-like precursor adx1 (adx1); Psort: bacterial cytoplasm --- Certainty= 0.209(Affirmative); COG0633 Fdx ferredoxin.
 
    
 0.771
petC
Cytochrome c1, heme protein precursor; Psort: bacterial inner membrane --- Certainty= 0.317(Affirmative); COG2857 CYT1 cytochrome c1.
 
 
 0.757
AMF_629
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial outside --- Certainty= 0.300(Affirmative); COG2867 Oligoketide cyclase/lipid transport protein.
    
  0.741
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase (panB); Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
       0.664
coxB
Cytochrome c oxidase subunit II (coxB); Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
  
 
 0.658
AMF_834
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.592(Affirmative); COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1.
 
 
 0.587
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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