STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coxWCytochrome C oxidase assembly protein (coxW); Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. (341 aa)    
Predicted Functional Partners:
ctaB
Cytochrome c oxidase assembly factor (ctaB); Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
  
 0.988
cox11
Cytochrome c oxidase assembly protein (cox11); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family.
 
 0.980
surf1
Surfeit locus protein 1 (surf1); Psort: bacterial inner membrane --- Certainty= 0.501(Affirmative); COG3346 - uncharacterized conserved protein.
 
 
 0.912
adx1
Ferredoxin [2Fe-2S] adrenodoxin-like precursor adx1 (adx1); Psort: bacterial cytoplasm --- Certainty= 0.209(Affirmative); COG0633 Fdx ferredoxin.
 
 
  
 0.812
msp5
Major surface protein 5 (MSP5); Psort: bacterial inner membrane --- Certainty= 0.391(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.837 Max cleavage site probability: 0.403 between pos. 26 and 27.
 
 
 0.758
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase (panB); Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
       0.666
petC
Cytochrome c1, heme protein precursor; Psort: bacterial inner membrane --- Certainty= 0.317(Affirmative); COG2857 CYT1 cytochrome c1.
 
 
 0.634
cycM
Cytochrome C (cycM); Psort: bacterial inner membrane --- Certainty= 0.412(Affirmative); COG3303 NrfA formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit.
 
   
 0.570
coxC
Cytochrome C oxidase, subunit III (coxC); Psort: bacterial inner membrane --- Certainty= 0.370(Affirmative); COG1845 CyoC heme/copper-type cytochrome/quinol oxidase, subunit 3.
  
  
 0.502
coxB
Cytochrome c oxidase subunit II (coxB); Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
  
  
 0.484
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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