Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMF_1031Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.501(Affirmative). (634 aa)    
Predicted Functional Partners:
grxC1
Glutaredoxin 3 (grxC1); Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
  
 
 0.863
dsbD
C-type cytochrome biogenesis protein (dsbD); Psort: bacterial inner membrane --- Certainty= 0.427(Affirmative); COG0526 TrxA thiol-disulfide isomerase and thioredoxins.
    
 
 0.803
dsbE
Thiol:disulfide interchange protein (dsbE); Psort: bacterial inner membrane --- Certainty= 0.414(Affirmative); COG0526 TrxA Thiol-disulfide isomerase and thioredoxins.
   
 0.763
AMF_357
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.448(Affirmative); COG0526 Thiol-disulfide isomerase and thioredoxins.
   
 0.763
AMF_002
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.582(Affirmative).
   
 0.747
groES
10 KD chaperonin (groES); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
   
 
 0.533
tdpX1
Thioredoxin peroxidase 1 (tdpX1); Psort: bacterial cytoplasm --- Certainty= 0.065(Affirmative); COG0450 AhpC peroxiredoxin.
  
 
 0.509
sodB
Fe superoxide dismutase (sodB); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
     
 0.481
polA
DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.456
trxA
Thioredoxin (trxA); Posrt: bacterial cytoplasm --- Certainty= 0.097(Affirmative); COG0526 TrxA thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
     
 0.439
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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