Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pepALeucyl aminopeptidase (pepA); Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (534 aa)    
Predicted Functional Partners:
gshB
Glutathione synthase (gshB); Psort: bacterial inner membrane --- Certainty= 0.185(Affirmative); COG0189 RimK glutathione synthase/ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.
   
 
 0.945
gshA
Glutamate-cysteine ligase (gshA); Psort: bacterial cytoplasm --- Certainty= 0.336(Affirmative); COG2918 GshA Gamma-glutamylcysteine synthetase.
     
  0.900
aatA
Aspartate aminotransferase A (aatA); Psort: bacterial cytoplasm --- Certainty= 0.178(Affirmative); COG0075 - serine-pyruvate aminotransferase/archaeal aspartate aminotransferase.
   
  0.843
metC
Cystathionine beta-lyase; Psort: bacterial inner membrane --- Certainty= 0.236(Affirmative); COG0626 cystathionine beta-lyases/cystathionine gamma-synthases.
   
 
  0.803
purN
Phosphoribosylglycinamide formyl transferase (purN); Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
       0.802
AMF_1056
Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.307(Affirmative).
       0.773
AMF_622
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.145(Affirmative); COG0006 Xaa-Pro aminopeptidase.
  
 
 0.538
pcxB
Protocatechuate 3,4-dioxygenase (pcxB); Psort: bacterial outer membrane --- Certainty= 0.935(Affirmative); COG3485 PcaH Protocatechuate 3,4-dioxygenase beta subunit.
       0.533
htpG
Heat shock protein (htpG); Molecular chaperone. Has ATPase activity.
   
   0.512
tpiA
Triosephosphate isomerase (tpiA); Psort: bacterial inner membrane --- Certainty= 0.251(Affirmative); COG0149 TpiA triosephosphate isomerase.
   
 
 0.441
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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