Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ntrYNitrogen regulation protein (ntrY); Psort: bacterial inner membrane --- Certainty= 0.567(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.998 Max cleavage site probability: 0.704 between pos. 32 and 33; COG0347 GlnK nitrogen regulatory protein PII. (695 aa)    
Predicted Functional Partners:
ntrX
Nitrogen assimilation regulatory protein (ntrX); Psort: bacterial cytoplasm --- Certainty= 0.262(Affirmative); COG3852 NtrB signal transduction histidine kinase, nitrogen specific.
 
 0.993
rnd
Ribonuclease D (rnd); Psort: bacterial inner membrane --- Certainty= 0.035(Affirmative); COG0349 Rnd ribonuclease D.
       0.808
czcR
Transcriptional activator protein (czcR); Psort: bacterial inner membrane --- Certainty= 0.143(Affirmative); COG0745 OmpR response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
    
 
 0.762
dhkA
Sensory box histidine kinase/response regulator (dhkA); Psort: bacterial inner membrane --- Certainty= 0.491(Affirmative); COG0642 Signal transduction histidine kinase.
 
 
 0.756
cspA
Cold shock protein (cspA); Psort: bacterial cytoplasm --- Certainty= 0.427(Affirmative); COG1278 CspC cold shock proteins.
     
 0.696
dksA
dnaK suppressor protein (dksA); Psort: bacterial cytoplasm --- Certainty= 0.549(Affirmative); COG1734 DksA DnaK suppressor protein.
 
     0.606
AMF_1013
NADH-ubiquinone oxidoreductase, putative; Psort: bacterial inner membrane --- Certainty= 0.102(Affirmative); COG0702 Predicted nucleoside-diphosphate-sugar epimerases.
  
     0.473
greA
Transcription elongation factor greA (greA); Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
      
 0.427
nuoL
NADH dehydrogenase I chain L (nuoL); Psort: bacterial inner membrane --- Certainty= 0.576(Affirmative); COG1009 NuoL NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.
      
 0.426
dnaN
DNA polymerase III beta chain (dnaN); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]
      
 0.423
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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