STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsbEThiol:disulfide interchange protein (dsbE); Psort: bacterial inner membrane --- Certainty= 0.414(Affirmative); COG0526 TrxA Thiol-disulfide isomerase and thioredoxins. (162 aa)    
Predicted Functional Partners:
ccmF
Cytochrome c-type biogenesis protein (ccmF); Psort: bacterial inner membrane --- Certainty= 0.529(Affirmative); COG1138 CcmF cytochrome c biogenesis factor.
 
  
 0.969
dsbD
C-type cytochrome biogenesis protein (dsbD); Psort: bacterial inner membrane --- Certainty= 0.427(Affirmative); COG0526 TrxA thiol-disulfide isomerase and thioredoxins.
 
 
 0.959
AMF_1031
Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.501(Affirmative).
   
 0.940
tdpX1
Thioredoxin peroxidase 1 (tdpX1); Psort: bacterial cytoplasm --- Certainty= 0.065(Affirmative); COG0450 AhpC peroxiredoxin.
  
 0.933
ccmC
Cytochrome c-type biogenesis protein (ccmC); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
  
 0.908
ccmE
Cytochrome c-type biogenesis protein (ccmE); Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
  
 0.899
AMF_482
Conserved hypothetical protein; Possible subunit of a heme lyase.
 
  
 0.877
msp5
Major surface protein 5 (MSP5); Psort: bacterial inner membrane --- Certainty= 0.391(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.837 Max cleavage site probability: 0.403 between pos. 26 and 27.
   
   0.844
pdhD
Dihydrolipoamide dehydrogenase (pdhD); Psort: bacterial inner membrane --- Certainty= 0.117(Affirmative).
   
  0.817
lpdA
Dihydrolipoamide dehydrogenase (lpdA); Psort: bacterial membrane --- Certainty= 0.512(Affirmative); COG1249 Lpd dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes.
   
  0.817
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.