STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMF_117Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.576(Affirmative); COG1593 Integral membrane protein, possible transporter. (880 aa)    
Predicted Functional Partners:
AMF_417
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; C-terminal end matches AMF_428; psort: bacterial periplasmic space --- Certainty= 0.294(Affirmative); COG2358 Predicted periplasmic binding protein.
 
    0.836
AMF_118
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.465(Affirmative).
       0.817
rpsF
30S ribosomal protein S6 (rpsF); Binds together with S18 to 16S ribosomal RNA.
       0.759
rpsR
Small subunit ribosomal protein S18 (rpsR); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
       0.759
rplI
Ribosomal protein L9 (rplI); Binds to the 23S rRNA.
       0.699
glyA
Glycine/serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.621
AMF_428
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; 65/65 identities with the C-terminal end of AMF_417 (from AA 275-339); psort: bacterial cytoplasm --- Certainty= 0.077(Affirmative); COG2358 Predicted periplasmic binding protein.
 
    0.575
acrD
Acriflavin resistance protein D (acrD); Psort: bacterial inner membrane --- Certainty= 0.722(Affirmative); COG0841 AcrB cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
     0.519
dsbE
Thiol:disulfide interchange protein (dsbE); Psort: bacterial inner membrane --- Certainty= 0.414(Affirmative); COG0526 TrxA Thiol-disulfide isomerase and thioredoxins.
       0.457
radA
DNA repair protein (radA); DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
       0.457
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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