STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyaYPutative CyaY protein; Psort: bacterial cytoplasm --- Certainty= 0.285(Affirmative); COG2114 CyaA Adenylate cyclase, family 3 (some proteins contain HAMP domain); Belongs to the frataxin family. (113 aa)    
Predicted Functional Partners:
nifU
Iron-sulfur cofactor synthesis protein (nifU); A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
    
 0.998
nifS-2
Putative cystine defulfurase (nifS-like protein); Duplicated gene; Similar to AMF_489; psort: bacterial inner membrane --- Certainty= 0.119(Affirmative); COG1104 cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.
   
 0.987
nifS
Cysteine desulfurase (nifS) (duplicated gene); Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
   
 0.979
hemH
Ferrochelatase (hemH); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
    
 0.966
adx1
Ferredoxin [2Fe-2S] adrenodoxin-like precursor adx1 (adx1); Psort: bacterial cytoplasm --- Certainty= 0.209(Affirmative); COG0633 Fdx ferredoxin.
     
 0.932
msbA2
ABC efflux transporter (msbA2); Psort: bacterial inner membrane --- Certainty= 0.397(Affirmative); COG1132 MdlB ABC-type multidrug/protein/lipid transport system, ATPase component.
   
   0.827
groEL
60 kD chaperonin (groEL); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
  0.784
AMF_021
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.234(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.646 Max cleavage site probability: 0.575 between pos. 27 and 28.
  
     0.744
AMF_093
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.317(Affirmative).
  
     0.724
AMF_602
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; Possible type IV secretion system protein (virB6); psort: bacterial inner membrane --- Certainty= 0.722(Affirmative); COG3704 Type IV secretory pathway, VirB6 components.
  
     0.709
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.